thrombin receptor peptide (42-47)

Known as: SFLLRN, thrombin (42-47) peptide, seryl-phenylalanyl--leucyl-leucyl-arginyl-asparagine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
010203019922018

Papers overview

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Highly Cited
2005
Highly Cited
2005
Thrombin activates protease-activated receptor-1 (PAR-1) by cleavage of the amino terminus to unmask a tethered ligand. Although… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE The importance of PAR-1 in blood vessel development has been demonstrated in knockout mice. As endothelial progenitor… (More)
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Highly Cited
2002
Highly Cited
2002
Activation of microglia, the resident macrophages in the CNS, plays a significant role in neuronal death or degeneration in a… (More)
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Highly Cited
2001
Highly Cited
2001
An imbalance of nitric oxide and endothelin plays an important role in cardiovascular disease. Thrombin exerts profound effects… (More)
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Highly Cited
2000
Highly Cited
2000
Although serine proteases and their receptors are best known for their role in blood coagulation and fibrinolysis, the CNS… (More)
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Highly Cited
1999
Highly Cited
1999
Platelet activation leads to secretion of granule contents and to the formation of microvesicles by shedding of membranes from… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The CD40 ligand (CD40L) on activated T cells and platelets may be activating matrix metalloproteinases, inducing… (More)
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Highly Cited
1999
Highly Cited
1999
Platelet activation leads to secretion of granule contents and to the formation of microvesicles by shedding of membranes from… (More)
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Highly Cited
1996
Highly Cited
1996
The Ca2+-sensitive 85-kDa cytosolic phospholipase A2 (cPLA2) is responsible for thrombin-stimulated mobilization of arachidonic… (More)
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Highly Cited
1993
Highly Cited
1993
Shortly after activation by either thrombin or the tethered ligand domain peptide SFLLRN, thrombin receptors undergo homologous… (More)
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