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tedizolid

Known as: torezolid, 3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one, 2-Oxazolidinone, 3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-yl)-3-Pyridinyl)Phenyl)-5-(Hydroxymethyl)-, (5R)- 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (3)

Anti-Bacterial AgentsOxazolidinonesTetrazoles
Bacterial InfectionsBreast Cancer Resistance Protein Inhibitors [MoA]Tedizolid:Susc:Pt:Isolate:OrdQnTedizolid:Susc:Pt:Isolate:OrdQn:Agar diffusion

Narrower (3)

SivextroTR 700tedizolid phosphate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Safety and Tolerability of More than Six Days of Tedizolid Treatment
Tedizolid has demonstrated its efficacy and safety in clinical trials; however, data concerning its tolerability in long-term… 
2018
2018
Evaluation of the ability of linezolid and tedizolid to eradicate intraosteoblastic and biofilm-embedded Staphylococcus aureus in the bone and joint infection setting
OBJECTIVES Prolonged use of linezolid for bone and joint infection (BJI) is limited by its long-term toxicity. The better safety… 
Highly Cited
2017
Highly Cited
2017
ECDC, EFSA and EMA Joint Scientific Opinion on a list of outcome indicators as regards surveillance of antimicrobial resistance and antimicrobial consumption in humans and food‐producing animals
Abstract ECDC, EFSA and EMA have jointly established a list of harmonised outcome indicators to assist EU Member States in… 
Review
2017
Review
2017
Future trends in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection: An in-depth review of newer antibiotics active against an enduring pathogen.
Review
2016
Review
2016
Methicillin-resistant Staphylococcus aureus infections: A review of the currently available treatment options.
2016
2016
Activity of Tedizolid in Methicillin-Resistant Staphylococcus epidermidis Experimental Foreign Body-Associated Osteomyelitis
ABSTRACT We developed a rat model of methicillin-resistant Staphylococcus epidermidis (MRSE) foreign body-associated… 
Review
2014
Review
2014
Tedizolid: a novel oxazolidinone for Gram-positive infections.
Despite the concerted efforts of modern medicine, infections due to gram-positive bacteria, such as skin and soft tissue… 
Highly Cited
2010
Highly Cited
2010
Elevated Linezolid Resistance in Clinical cfr-Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3
ABSTRACT Resistance to linezolid (LZD) occurs through mutations in 23S rRNA and ribosomal proteins L3 and L4 or through… 
Highly Cited
2009
Highly Cited
2009
Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)
ABSTRACT TR-700 (torezolid), the active moiety of the novel oxazolidinone phosphate prodrug TR-701, is highly potent against gram… 
Highly Cited
2009
Highly Cited
2009
Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines.
BACKGROUND AND AIMS Optimal treatment of infections caused by Staphylococcus aureus, Listeria monocytogenes and Legionella… 
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