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TR 700
Known as:
TR-700
National Institutes of Health
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Related topics
1 relation
Broader (1)
tedizolid
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
In vitro activity of tedizolid (TR-700) against linezolid-resistant staphylococci.
I. Rodríguez-Avial
,
E. Culebras
,
C. Betriú
,
Gracia Morales
,
I. Peña
,
J. Picazo
Journal of Antimicrobial Chemotherapy
2012
Corpus ID: 205148648
OBJECTIVES To compare the activity of tedizolid (formally known as torezolid and TR-700) with that of 15 agents against a…
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Highly Cited
2012
Highly Cited
2012
In Vitro Activity and Microbiological Efficacy of Tedizolid (TR-700) against Gram-Positive Clinical Isolates from a Phase 2 Study of Oral Tedizolid Phosphate (TR-701) in Patients with Complicated…
P. Prokocimer
,
P. Bien
,
C. Deanda
,
C. Pillar
,
K. Bartizal
Antimicrobial Agents and Chemotherapy
2012
Corpus ID: 19688091
ABSTRACT Tedizolid (TR-700, formerly torezolid) is the active moiety of the prodrug tedizolid phosphate (TR-701), a next…
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Highly Cited
2011
Highly Cited
2011
In Vivo Pharmacodynamics of Torezolid Phosphate (TR-701), a New Oxazolidinone Antibiotic, against Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Strains in a Mouse Thigh…
A. Louie
,
Weiguo Liu
,
R. Kulawy
,
G. Drusano
Antimicrobial Agents and Chemotherapy
2011
Corpus ID: 24228624
ABSTRACT Torezolid phosphate (TR-701) is the phosphate monoester prodrug of the oxazolidinone TR-700 which demonstrates potent in…
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Highly Cited
2010
Highly Cited
2010
Comparative In Vitro Antimicrobial Activities of Torezolid (TR-700), the Active Moiety of a New Oxazolidinone, Torezolid Phosphate (TR-701), Determination of Tentative Disk Diffusion Interpretive…
Steven D. Brown
,
M. Traczewski
Antimicrobial Agents and Chemotherapy
2010
Corpus ID: 23258075
ABSTRACT This study assessed the spectrum of activity of torezolid (TR-700), the active moiety of torezolid phosphate (TR-701…
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Highly Cited
2009
Highly Cited
2009
Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)
Jeffrey B Locke
,
M. Hilgers
,
K. Shaw
Antimicrobial Agents and Chemotherapy
2009
Corpus ID: 28811987
ABSTRACT TR-700 (torezolid), the active moiety of the novel oxazolidinone phosphate prodrug TR-701, is highly potent against gram…
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Highly Cited
2009
Highly Cited
2009
In Vitro Activity of TR-700, the Active Ingredient of the Antibacterial Prodrug TR-701, a Novel Oxazolidinone Antibacterial Agent
R. Schaadt
,
Debora Sweeney
,
D. Shinabarger
,
G. Zurenko
Antimicrobial Agents and Chemotherapy
2009
Corpus ID: 8996109
ABSTRACT TR-701 is the prodrug of the microbiologically active molecule TR-700, a novel orally and intravenously administered…
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Highly Cited
2009
Highly Cited
2009
Activity of oxazolidinone TR-700 against linezolid-susceptible and -resistant staphylococci and enterococci.
D. Livermore
,
S. Mushtaq
,
M. Warner
,
N. Woodford
Journal of Antimicrobial Chemotherapy
2009
Corpus ID: 10535800
BACKGROUND TR-700 is the active moiety of TR-701 (DA-7157), a new oral/intravenous oxazolidinone prodrug. We examined its…
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Highly Cited
2009
Highly Cited
2009
Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines.
S. Lemaire
,
F. Van Bambeke
,
P. Appelbaum
,
P. Tulkens
Journal of Antimicrobial Chemotherapy
2009
Corpus ID: 14592389
BACKGROUND AND AIMS Optimal treatment of infections caused by Staphylococcus aureus, Listeria monocytogenes and Legionella…
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2009
2009
TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens.
Ronald N. Jones
,
Gary J. Moet
,
H. Sader
,
R. Mendes
,
M. Castanheira
Journal of Antimicrobial Chemotherapy
2009
Corpus ID: 19415278
BACKGROUND TR-700, the active component of the oxazolidinone prodrug TR-701, has demonstrated potent activity against numerous…
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Highly Cited
2008
Highly Cited
2008
In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains
K. Shaw
,
S. Poppe
,
+5 authors
G. Zurenko
Antimicrobial Agents and Chemotherapy
2008
Corpus ID: 1043952
ABSTRACT TR-701 is the orally active prodrug of TR-700, a novel oxazolidinone that demonstrates four- to eightfold-greater…
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