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TR 700

Known as: TR-700 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

tedizolid

Papers overview

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2013
2013
Activity of Tedizolid (TR-700) against Well-Characterized Methicillin-Resistant Staphylococcus aureus Strains of Diverse Epidemiological Origins
ABSTRACT The in vitro activities of tedizolid and 10 antistaphylococcal agents were compared against 111 methicillin-resistant… Expand
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Highly Cited
2012
Highly Cited
2012
In Vitro Activity and Microbiological Efficacy of Tedizolid (TR-700) against Gram-Positive Clinical Isolates from a Phase 2 Study of Oral Tedizolid Phosphate (TR-701) in Patients with Complicated…
ABSTRACT Tedizolid (TR-700, formerly torezolid) is the active moiety of the prodrug tedizolid phosphate (TR-701), a next… Expand
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Highly Cited
2012
Highly Cited
2012
In vitro activity of tedizolid (TR-700) against linezolid-resistant staphylococci.
OBJECTIVES To compare the activity of tedizolid (formally known as torezolid and TR-700) with that of 15 agents against a… Expand
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Highly Cited
2010
Highly Cited
2010
Comparative In Vitro Antimicrobial Activities of Torezolid (TR-700), the Active Moiety of a New Oxazolidinone, Torezolid Phosphate (TR-701), Determination of Tentative Disk Diffusion Interpretive…
ABSTRACT This study assessed the spectrum of activity of torezolid (TR-700), the active moiety of torezolid phosphate (TR-701… Expand
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Highly Cited
2009
Highly Cited
2009
In Vitro Activity of TR-700, the Active Ingredient of the Antibacterial Prodrug TR-701, a Novel Oxazolidinone Antibacterial Agent
ABSTRACT TR-701 is the prodrug of the microbiologically active molecule TR-700, a novel orally and intravenously administered… Expand
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Highly Cited
2009
Highly Cited
2009
Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)
ABSTRACT TR-700 (torezolid), the active moiety of the novel oxazolidinone phosphate prodrug TR-701, is highly potent against gram… Expand
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Highly Cited
2009
Highly Cited
2009
Activity of oxazolidinone TR-700 against linezolid-susceptible and -resistant staphylococci and enterococci.
BACKGROUND TR-700 is the active moiety of TR-701 (DA-7157), a new oral/intravenous oxazolidinone prodrug. We examined its… Expand
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Highly Cited
2009
Highly Cited
2009
Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines.
BACKGROUND AND AIMS Optimal treatment of infections caused by Staphylococcus aureus, Listeria monocytogenes and Legionella… Expand
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2009
2009
TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens.
BACKGROUND TR-700, the active component of the oxazolidinone prodrug TR-701, has demonstrated potent activity against numerous… Expand
Highly Cited
2008
Highly Cited
2008
In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains
ABSTRACT TR-701 is the orally active prodrug of TR-700, a novel oxazolidinone that demonstrates four- to eightfold-greater… Expand
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