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taltobulin

An analogue of the naturally occurring tripeptide hemiasterlin, with potential antimitotic and antineoplastic activities. Taltobulin binds tubulin in… 
National Institutes of Health

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HTI-286Microtubule Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules s
Antibody-drug conjugates (ADCs) have achieved great success in cancer therapy in recent years. Some peptidyl microtubule… 
2011
2011
The Dolastatins: Novel Antitumor Agents from Dolabella auricularia
2010
2010
Absolute configurations of tubulin inhibitors taltobulin (HTI-286) and HTI-042 characterized by X-ray diffraction analysis and NMR studies.
2006
2006
Mapping the bound conformation and protein interactions of microtubule destabilizing peptides by STD-NMR spectroscopy.
2005
2005
Taltobulin : Oncolytic drug Prop INN tubulin polymerization inhibitor antimitotic drug
Antimicrotubule agents are among the most effective drugs for the treatment of breast, ovarian and other forms of cancer. Two… 
2004
2004
Gateways to clinical trials.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
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