HTI-286

Known as: HTI 286, HTI286 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
02420032017

Papers overview

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2010
2010
The stereochemistry of the tubulin inhibitors taltobulin HTI-286 (2) and HTI-042 (3) was determined by utilizing the DPFGSE 1D… (More)
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2009
2009
Clinical results of current intravesical chemotherapeutics are insufficient, and novel and safe intravesical options for high… (More)
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2008
2008
Therapeutic resistance is the underlying cause for most cancer deaths and a major problem associated with treatment of metastatic… (More)
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2008
2008
PURPOSE HTI-286 is a fully synthetic analogue of the natural tripeptide hemiasterlin that inhibits tubulin polymerization and has… (More)
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2005
2005
A binding mode of HTI-286, a synthetic analogue of the peptidic antimitotic agent hemiasterlin, to tubulin is proposed. The… (More)
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2004
2004
Hemiasterlins are sponge-derived tripeptides that inhibit cell growth by depolymerizing existing microtubules and inhibiting… (More)
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2004
2004
Modifications of the D-piece carboxylic acid group of the hemiasterlin analog HTI-286 gave tubulin inhibitors which were potent… (More)
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2004
2004
HTI-286 is a synthetic analogue of the natural product hemiasterlin. HTI-286 is a potent antitumor agent that induces tubulin… (More)
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2003
2003
Hemiasterlin is a natural product derived from marine sponges that, like other structurally diverse peptide-like molecules, binds… (More)
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2003
2003
HTI-286 is a synthetic analogue of the natural product hemiasterlin and is a potent antimitotic agent. HTI-286 inhibits the… (More)
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