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HTI-286

Known as: HTI 286, HTI286 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The spatial weights for electrodes called common spatial pattern (CSP) are known to be effective in EEG signal classification for… Expand
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2009
2009
Clinical results of current intravesical chemotherapeutics are insufficient, and novel and safe intravesical options for high… Expand
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2008
2008
Therapeutic resistance is the underlying cause for most cancer deaths and a major problem associated with treatment of metastatic… Expand
2008
2008
Purpose: HTI-286 is a fully synthetic analogue of the natural tripeptide hemiasterlin that inhibits tubulin polymerization and… Expand
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Review
2008
Review
2008
The chemical, biological and ecological diversity of the marine ecosystem has contributed immensely in the discovery of extremely… Expand
Highly Cited
2006
Highly Cited
2006
Resistance to paclitaxel-based therapy is frequently encountered in the clinic. The mechanisms of intrinsic or acquired… Expand
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2004
2004
Modifications of the D-piece carboxylic acid group of the hemiasterlin analog HTI-286 gave tubulin inhibitors which were potent… Expand
2004
2004
HTI-286, a synthetic analogue of hemiasterlin, depolymerizes microtubules and is proposed to bind at the Vinca peptide site in… Expand
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Highly Cited
2003
Highly Cited
2003
Hemiasterlin is a natural product derived from marine sponges that, like other structurally diverse peptide-like molecules, binds… Expand
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2003
2003
HTI-286 is a synthetic analogue of the natural product hemiasterlin and is a potent antimitotic agent. HTI-286 inhibits the… Expand