tallimustine

Known as: 1H-Pyrrole-2-carboxamide, N-(5-(((3-amino-3-iminopropyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-4-(((4-((4-(bis(2-chloroethyl)amino)benzoyl)amino)-1-methyl-1H-pyrrol-2-yl)carbonyl)amino)-1-methyl-, N-deformyl-N-(4-N-N,N-bis(2-choroethylamino)benzoyl)distamycin 
A benzoyl mustard derivative of the antiviral agent distamycin A with potential antineoplastic activity. Tallimustine selectively binds to A-T rich… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or N-(3-chloro-2-hydroxypropyl… Expand
Is this relevant?
2001
2001
Human leukaemic K562 cells can be induced in vitro to erythroid differentiation by a variety of chemical compounds, including… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Ecteinascidin-743 (ET-743) is a tetrahydroisoquinoline alkaloid isolated from the tunicate Ecteinascidia turbinata currently… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
1998
1998
Tallimustine [PNU 152241 (FCE 24517)] is a synthetic derivative of the DNA minor groove binder distamycin A, in which the NH2… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Nucleotide excision repair (NER) is one of the major DNA repair systems in mammalian cells, able to remove a broad spectrum of… Expand
Is this relevant?
1995
1995
FCE 24517, a novel distamycin derivative possessing potent antitumor activity, is under initial clinical investigation in Europe… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1995
1995
The antibiotic distamycin A is a DNA minor groove binding drug (MGB) that recognizes a stretch of at least four ATs. The… Expand
Is this relevant?
1995
1995
The CCAAT box is one of the most common promoter elements. The evolutionarily conserved heteromeric factor NF-Y binds this… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
1994
1994
BACKGROUND Tallimustine, a benzoyl nitrogen mustard derivative of the antiviral agent distamycin A, is a new alkylating agent… Expand
Is this relevant?
1989
1989
Echinocandin B (ECB) is a lipopeptide antifungal agent produced by several species of Aspergillus. The lipid side chain of cyclic… Expand
Is this relevant?