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tallimustine

Known as: 1H-Pyrrole-2-carboxamide, N-(5-(((3-amino-3-iminopropyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-4-(((4-((4-(bis(2-chloroethyl)amino)benzoyl)amino)-1-methyl-1H-pyrrol-2-yl)carbonyl)amino)-1-methyl-, N-deformyl-N-(4-N-N,N-bis(2-choroethylamino)benzoyl)distamycin 
A benzoyl mustard derivative of the antiviral agent distamycin A with potential antineoplastic activity. Tallimustine selectively binds to A-T rich… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antineoplastic AgentsAntineoplastic Agents, AlkylatingDistamycinsNitrogen Mustard Compounds

Narrower (1)

FCE 24517

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Ordering of N-(4-n-butyloxybenzylidene)-4'-n-ethylaniline at nematic-isotropic transition temperature: A computational analysis
A computational analysis of ordering in liquid crystalline compound N-(4-n-butyloxybenzylidene)-4'-n-ethylaniline (40.2) was… 
2003
2003
Induction of γ-globin gene expression by tallimustine analogs in human erythroid cells
Modulation of γ-globin gene expression is of relevance for the treatment of β-thalassemia and sickle cell anemia. We studied the… 
2002
2002
Synthesis and Characterization of New Aromatic Polyamides Having Pendent N-(4-n-Alkylphenyl)imido Group
1997
1997
Cytotoxic and antitumor activity of MEN 10710, a novel alkylating derivative of distamycin
MEN 10710 is a new synthetic distamycin derivative possessing four pyrrole rings and a bis-(2-chloroethyl)-aminophenyl moiety… 
1997
1997
SYNTHESIS OF N, N'-BIS N-(4-N-METHYLCARBAMYL-OXYMETHYLTHIOXANTHEN-9-ON-1-YL) AMINOETHYL-PIPERAZINE OF POSSIBLE ANTITUMOR ACTIVITY
1997
1997
Combination of the New Minor Groove and Melphalan Alkylator Tallimustine
The benzoyl nitrogen mustard derivative of distamycin A, tallimustine, belongs to a new class of alkylating agents, known as DNA… 
1996
1996
The alkylating antitumor drug tallimustine does not induce DNA repair.
Tallimustine, an alkylating benzoyl mustard derivative of distamycin A (FCE 24517), is a novel anti-tumor agent. Both its… 
1996
1996
3-methyladenine-DNA-glycosylase and O6-alkyl guanine-DNA-alkyltransferase activities and sensitivity to alkylating agents in human cancer cell lines.
The activities and the expression of 3-methyladenine glycosylase (3-meAde gly) and O6-alkylguanine-DNA-alkyltransferase (O6 ATase… 
1994
1994
Comparison of Liquid Crystalline Behavior of N-(4-n-Alkyloxybenzylidene)-$4^{\prime}$-n-butylanilines and N-(4-n-Alkyloxybenzylidene)-$4^{\prime}$-p-aminocinnamates
1987
1987
Thermal-conductivity studies near the smectic-A-smectic-C transition in a liquid-crystal compound.
High-resolution thermal-conductivity and heat-capacity studies were carried out on the same sample in the vicinity of the smectic… 
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