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Human genetics has indicated a causal role for the protein α-synuclein in the pathogenesis of familial Parkinson's disease (PD… Expand Neurotransmission is based on the exocytic release of neurotransmitters from synaptic vesicles (SVs) at nerve terminals and the… Expand Wnt signaling is essential for neuronal development and the maintenance of the developing nervous system. Recent studies… Expand The synaptic vesicle cycle is vital for sustained neurotransmitter release. It has been assumed that functional synaptic vesicles… Expand Membrane vesicle cycling is orchestrated through the combined actions of proteins and lipids. At neuronal synapses, this… Expand Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the presynaptic active zone of nerve terminals. To… Expand Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the presynaptic active zone of nerve terminals. To… Expand Cone photoreceptors tonically release neurotransmitter in the dark through a continuous cycle of exocytosis and endocytosis. Here… Expand What are the molecular mechanisms that guide the synaptic vesicle pathway? The components of synaptic vesicles have been largely… Expand The synaptic vesicle cycle at the nerve terminal consists of vesicle exocytosis with neuro-transmitter release, endocytosis of… Expand