sulforafan

Known as: sulforaphane, (R)-, 1-isothiocyanato-4-methylsulfinyl-butane, 1-isothiocyanato-4-methylsulphinylbutane 
A naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin… (More)
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Cruciferous vegetables are a rich source of glucosinolates and their hydrolysis products, including indoles and isothiocyanates… (More)
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Review
2005
Review
2005
Drug metabolizing enzymes (DMEs) play central roles in the metabolism, elimination and detoxification of xenobiotics and drugs… (More)
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Highly Cited
2004
Highly Cited
2004
The bZIP transcription factor Nrf2 controls a genetic program that protects cells from oxidative damage and maintains cellular… (More)
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Highly Cited
2003
Highly Cited
2003
A common feature of diverse chemopreventive agents is the ability to activate expression of a genetic program that protects cells… (More)
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Highly Cited
2003
Highly Cited
2003
Keap1 is a negative regulator of Nrf2, a bZIP transcription factor that mediates adaptation to oxidative stress. Previous studies… (More)
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Highly Cited
2002
Highly Cited
2002
Coordinate induction of phase 2 proteins and elevation of glutathione protect cells against the toxic and carcinogenic effects of… (More)
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Highly Cited
2002
Highly Cited
2002
Electrophiles formed during metabolic activation of chemical carcinogens and reactive oxygen species generated from endogenous… (More)
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Highly Cited
2002
Highly Cited
2002
Gastric infection with Helicobacter pylori is a cosmopolitan problem, and is especially common in developing regions where there… (More)
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Highly Cited
1997
Highly Cited
1997
Induction of phase 2 detoxication enzymes [e.g., glutathione transferases, epoxide hydrolase, NAD(P)H: quinone reductase, and… (More)
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Highly Cited
1992
Highly Cited
1992
Consumption of vegetables, especially crucifers, reduces the risk of developing cancer. Although the mechanisms of this… (More)
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