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Isothiocyanates

Known as: Isothiocyanates [Chemical/Ingredient], isothiocyanate 
Organic compounds with the general formula R-NCS.
National Institutes of Health

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Narrower (45)

1,3,6-trisulfonylpyrene 8-isothiocyanate1,4-phenylene diisothiocyanate10-isothiocyano-4-cadinene2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate
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In Bloodagonistsantagonists & inhibitorschemical synthesis

Broader (1)

Sulfur Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Glucosinolates and isothiocyanates in health and disease.
Glucosinolates and isothiocyanates have both been objects of research for more than half a century. Interest in these unique… Expand
Review
2008
Review
2008
Glucosinolates, isothiocyanates and human health
Concurrent with the increase in our knowledge of the genetic and environmental factors that lead to glucosinolate accumulation in… Expand
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Highly Cited
2006
Highly Cited
2006
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.
Reactive oxygen species (ROS) stimulate cell proliferation and induce genetic instability, and their increase in cancer cells is… Expand
Highly Cited
2004
Highly Cited
2004
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
Wasabi, horseradish and mustard owe their pungency to isothiocyanate compounds. Topical application of mustard oil (allyl… Expand
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Highly Cited
2001
Highly Cited
2001
Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans.
Broccoli sprouts are a rich source of glucosinolates and isothiocyanates that induce phase 2 detoxication enzymes, boost… Expand
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Review
2000
Review
2000
INHIBITION OF CARCINOGENESIS BY ISOTHIOCYANATES*
  • S. Hecht
  • Drug metabolism reviews
  • 2000
    • Corpus ID: 19351779
Isothiocyanates occur as conjugates in a wide variety of cruciferous vegetables. Consumption of normal amounts of these… Expand
Highly Cited
2000
Highly Cited
2000
Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China
BACKGROUND Dietary isothiocyanates inhibit lung carcinogenesis in laboratory animals but human data are limited. Glutathione S… Expand
Highly Cited
2000
Highly Cited
2000
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells.
Sulforaphane is an isothiocyanate that is present naturally in widely consumed vegetables and has a particularly high… Expand
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Highly Cited
1998
Highly Cited
1998
Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables.
Isothiocyanates and their naturally occurring glucosinolate precursors are widely consumed as part of a diet rich in cruciferous… Expand
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Review
1994
Review
1994
Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms.
Organic isothiocyanates block the production of tumors induced in rodents by diverse carcinogens (polycyclic aromatic… Expand
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