stress-induced premature senescence

Known as: SIPS 
A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
05010019542016

Papers overview

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Review
2018
Review
2018
  • João Pedro de Magalhães, João F. Passos
  • Mechanisms of Ageing and Development
  • 2018
Cellular senescence was first described by Hayflick and Moorhead in the 1960s as the irreversible arrest of cells following… (More)
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2012
2012
Stress-induced premature senescence (SIPS) of endothelial cells (ECs) has emerged as a contributor to global EC dysfunction. One… (More)
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Highly Cited
2009
Highly Cited
2009
We investigated miRNA expression changes associated with stress-induced premature senescence (SIPS) in primary cultures of human… (More)
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2008
2008
INTRODUCTION Chronic and debilitating low back pain is a common condition and a huge economic burden. Many cases are attributed… (More)
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Highly Cited
2007
Highly Cited
2007
Yeast Sir2 plays critical roles in gene silencing, stress resistance and longevity. Mammalian Sirt1 NAD(+)-dependent protein… (More)
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Highly Cited
2005
Highly Cited
2005
Premature senescence of human diploid fibroblasts (HDFs) can be induced by exposures to a variety of oxidative stress and DNA… (More)
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2004
2004
In addition to replicative senescence, normal diploid fibroblasts undergo stress-induced premature senescence (SIPS) in response… (More)
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Highly Cited
2002
Highly Cited
2002
Cells subjected to sub-lethal doses of stress such as irradiation or oxidative damage enter a state that closely resembles… (More)
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2002
2002
Exposure of human proliferative cells to subcytotoxic stress triggers stress-induced premature senescence (SIPS) which is… (More)
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Highly Cited
1977
Highly Cited
1977
Significant differences in both specificity and avidity of anti-DNA antibodies were observed in the sera of groups of patients… (More)
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