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squalestatin 1

Known as: zaragozic acid A 
 
National Institutes of Health

Papers overview

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2010
2010
Farnesyl pyrophosphate (FPP), a key intermediate in the mevalonate pathway and protein farnesylation, can act as an agonist for… Expand
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2008
2008
Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a critical role in cholesterol metabolism by enhancing the… Expand
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2002
2002
Because our previous studies indicated that squalestatin 1 treatment induces CYP2B expression in primary cultures of rat… Expand
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1999
1999
The activity of HMG-CoA reductase (HMGR) is tightly regulated, in part through post-transcriptional mechanisms that are mediated… Expand
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1998
1998
Abstract A Phoma sp., known to produce the pharmaceutically active metabolites squalestatin 1 (S1) and squalestatin 2 (S2), was… Expand
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1998
1998
The effects of treatment with squalestatin 1, a potent inhibitor of squalene synthase, the first committed enzyme of sterol… Expand
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1995
1995
The effect of squalestatin 1 (SQ) on squalene synthase and other enzymes utilizing farnesyl pyrophosphate (F-P-P) as substrate… Expand
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1995
1995
Evidence has been obtained indicating that free farnesol (F-OH) can be utilized for isoprenoid biosynthesis in mammalian cells… Expand
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1994
1994
The effects of squalestatin 1 on rat brain and liver homogenates and on Chinese hamster ovary tissue culture cells have been… Expand
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1993
1993
synthetase (EC 2.5.1.21) is a microsomal enzyme which catalyzes the two sequential reactions: head-to-head condensation of… Expand
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