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Bridged Bicyclo Compounds, Heterocyclic

Known as: Heterocyclic Bicyclo Compounds, Bicyclo Compounds, Heterocyclic, Heterocyclic Compounds, Bicyclic 
Heterocyclic compounds that contain two rings that share two non-adjacent atoms in common.
National Institutes of Health

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BMS 641988BPR1K653CD 222CHIBA 1001
antagonists & inhibitorschemical synthesis

Papers overview

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Review
2015
Review
2015
Synthesis of imidazo[1,2-a]pyridines: a decade update.
Imidazopyridine is one of the important fused bicyclic 5-6 heterocycles and it is recognized as a "drug prejudice" scaffold due… 
Review
2014
Review
2014
Metal-organic frameworks as solid catalysts for the synthesis of nitrogen-containing heterocycles.
Metal-organic frameworks (MOFs) are finding increasing application as solid catalysts for liquid phase reactions leading to the… 
Highly Cited
2011
Highly Cited
2011
Asymmetric catalysis of Diels-Alder reactions with in situ generated heterocyclic ortho-quinodimethanes.
The Diels-Alder reaction is probably the most powerful technology in the synthetic repertoire for single-step constructions of… 
Highly Cited
2007
Highly Cited
2007
Rapid intramolecular heterolytic dihydrogen activation by a four-membered heterocyclic phosphane-borane adduct.
A four-membered cyclic intramolecular phosphane-borane adduct activates dihydrogen to yield the respective ethylene-bridged… 
Review
2007
Review
2007
The chemistry of functionalised N-heterocyclic carbenes.
This tutorial review presents the synthesis, chemistry and applications of functionalised N-heterocyclic carbenes NHC and their… 
Review
2004
Review
2004
Review: Dietary Flavonoids and Cancer Risk: Evidence From Human Population Studies
Abstract: High dietary intake of fruits and vegetables is consistently associated with a reduced risk of common human cancers… 
Highly Cited
2000
Highly Cited
2000
6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
As part of our continuing search for potential anticancer candidates among 2-phenyl-4-quinolones and 2-phenyl-4-quinazolinones… 
Highly Cited
1994
Highly Cited
1994
Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.
The metabolic activation of food-borne heterocyclic amines to colon carcinogens in humans is hypothesized to occur via N… 
Review
1992
Review
1992
Food-derived mutagens and carcinogens.
Cooked food contains a variety of mutagenic heterocyclic amines. All the mutagenic heterocyclic amines tested were carcinogenic… 
Review
1991
Review
1991
Carcinogenicities of heterocyclic amines in cooked food.
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