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BPR1K653

National Institutes of Health

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2 relations

Broader (2)

Bridged Bicyclo Compounds, HeterocyclicPhenylurea Compounds

Papers overview

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2018
2018
Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition.
2017
2017
Abstract 3233: Design and synthesis of BPR1K653 and its derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition
2011
2011
BPR1K653, a Novel Aurora Kinase Inhibitor, Exhibits Potent Anti-Proliferative Activity in MDR1 (P-gp170)-Mediated Multidrug-Resistant Cancer Cells
Background Over-expression of Aurora kinases promotes the tumorigenesis of cells. The aim of this study was to determine the… 
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