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sorafenib tosylate

Known as: 4-(4-(3-(4-Chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic Acid Methyamide-4-methylbenzenesulfonate Tosylate 
The tosylate salt of sorafenib, a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical… 
National Institutes of Health

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17-N-allylamino-17-demethoxygeldanamycin/sorafenibAngiogenesis InhibitionBRAF protein, humanFLT3 protein, human

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Papers overview

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2016
2016
Method for preparing sorafenib tosylate
The invention discloses a method for preparing sorafenib tosylate. The method comprises the following steps: reacting p… 
2015
2015
Β-crystalline form of naputinib tosylate, preparation method therefor and pharmaceutical composition containing same
The present invention providesβ-crystalline form of 2 crystalline hydrate of compound N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3… 
2014
2014
Sorafenib f or the treatment of intermediate-advanced hepatocellular carcinomas: its safety and prognostic factors
Objective To discuss the safety and prognostic factors of sorafenib in treating intermediateadvanced hepatocellular carcinoma(HCC… 
2013
2013
DEVELOPMENT OF NEW VALIDATED METHOD FOR THE DETERMINATION OF SULTAMICILLIN TOSYLATE IN TABLET DOSAGE FORMS BY RP-HPLC
This paper presents a RP-HPLC method for the estimation of Sultamicillin Tosylate in tablets. The process was carried out on C18… 
2012
2012
Valutazione precoce della risposta a Sorafenib nel Carcinoma Epatocellulare mediante quantificazione dell'Ecografia con contrasto con software Sonotumor
Scopo dello studio: Stabilire se cambiamenti della perfusione di una lesione target di epatocarcinoma (HCC), valutati… 
2012
2012
Radioembolisation von Lebertumoren: hepatopulmonale Shuntreduktion nach Sorafenib-Therapie
2012
2012
Method Development And Validation of Sultamcillin Tosylate in Tablet Dosage form by RP-HPLC and HPTLC
AIM: To develop and validate a new isocratic RP-HPLC and HPTLC methods for the determination of sultamcillin tosylate in tablet… 
Review
2010
Review
2010
Palladium-Catalyzed Sonogashira Coupling of Aryl Mesylates and ACHTUNGTRENNUNG osylates
Aryl alkynes are important synthetic precursors and subunits for a range of pharmaceutically attractive and valued materials… 
2004
2004
The preparation of Sultamicillin Tosylate gelatin microspheres and its HPLC determination
1999
1999
Synthesis of (2S, 5S)- trans-5-(4- fluorophenoxymethyl) -2-(1-N-hydroxy ureidyl-3-butyn-4-yl) -tetrahydrofuran– (CMI-977)
Abstract