Nexavar

 

Topic mentions per year

Topic mentions per year

2006-2018
05101520062018

Papers overview

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2015
2015
Prior tumor cell studies have shown that the drugs sorafenib (Nexavar) and regorafenib (Stivarga) reduce expression of the… (More)
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Highly Cited
2011
Highly Cited
2011
Pemetrexed (ALIMTA, Lilly) is a folate antimetabolite that has been approved by the U.S. Food and Drug Administration for the… (More)
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2010
2010
The majority of kinase inhibitors developed to date are competitive inhibitors that target the ATP binding site; however, recent… (More)
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2010
2010
Signal transducers and activators of transcription 3 (STAT3) is constitutively active in human pancreatic cancer cells and can… (More)
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2009
2009
Chronic eosinophilic leukemia (CEL) is a rare myeloproliferative neoplasm characterized by the FIP1L1-PDGFRA fusion gene, variant… (More)
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2008
2008
 
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Sorafenib (Nexavar) is an oral multi-kinase inhibitor that targets tumor growth and angiogenesis. This phase II study… (More)
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Highly Cited
2007
Highly Cited
2007
Activating internal tandem duplication (ITD) insertions in the juxtamembrane domain of the FLT3 tyrosine kinase are found in… (More)
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Highly Cited
2006
Highly Cited
2006
Angiogenesis and signaling through the RAF/mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase (MEK)/ERK… (More)
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Highly Cited
2006
Highly Cited
2006
Activating mutations in Ras and B-RAF were identified in several human cancers. In addition, several receptor tyrosine kinases… (More)
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