FLT3 protein, human

Known as: CD135 Antigen, Fetal Liver Kinase-2, STK-1 kinase, human 
Receptor-type tyrosine-protein kinase FLT3 (993 aa, ~113 kDa) is encoded by the human FLT3 gene. This protein plays a role in tyrosine… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Mutations of the type III receptor tyrosine kinase FLT3 occur in approximately 30% of acute myeloid leukemia patients and lead to… (More)
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Review
2013
Review
2013
Hepatocellular carcinoma (HCC) is one of the most common and aggressive human cancers worldwide. HCC is an example of… (More)
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Highly Cited
2009
Highly Cited
2009
Adoptive transfer of human hematopoietic stem cells (HSCs) into mice lacking T, B and natural killer (NK) cells leads to… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Cytogenetics is the primary outcome predictor in acute myeloid leukemia (AML). Metaphase cytogenetics (MC) detects an… (More)
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Review
2007
Review
2007
Growth factors and mitogens use the Ras/Raf/MEK/ERK signaling cascade to transmit signals from their receptors to regulate gene… (More)
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Highly Cited
2004
Highly Cited
2004
The RAS/RAF signaling pathway is an important mediator of tumor cell proliferation and angiogenesis. The novel bi-aryl urea BAY… (More)
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Highly Cited
2001
Highly Cited
2001
Clonogenic multipotent mouse hematopoietic stem cells (HSCs) and progenitor cells are contained within the c-kit(+) (K) lineage… (More)
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Highly Cited
2000
Highly Cited
2000
STI571 (formerly known as CGP 57148B) is a protein-tyrosine kinase inhibitor that is currently in clinical trials for the… (More)
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Highly Cited
2000
Highly Cited
2000
The receptor tyrosine kinase Flt3 plays an important role in proliferation and survival of hematopoietic stem and progenitor… (More)
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Review
1996
Review
1996
The novel hematopoietic growth factor FLT3 ligand (FL) is the cognate ligand for the FLT3, tyrosine kinase receptor (R), also… (More)
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