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sodium-potassium-chloride cotransporter 1 protein

Known as: Transport Protein, BSC2, NKCC1 Transport Protein, Protein, BSC2 Transport 
Na-K-Cl transporter ubiquitously expressed. It plays a key role in salt secretion in epithelial cells and cell volume regulation in nonepithelial… 
National Institutes of Health

Related topics

Related topics

19 relations
Cellular MembraneIn BloodIntegral Membrane ProteinsIonophore activity

Broader (1)

SLC12A2 gene

Papers overview

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Highly Cited
2012
Highly Cited
2012
Metabolic Communication between Astrocytes and Neurons via Bicarbonate-Responsive Soluble Adenylyl Cyclase
Highly Cited
2010
Highly Cited
2010
Role of the WNK-activated SPAK kinase in regulating blood pressure
Mutations within the with‐no‐K(Lys) (WNK) kinases cause Gordon's syndrome characterized by hypertension and hyperkalaemia. WNK… 
Highly Cited
2007
Highly Cited
2007
Direct Protein Kinase C-dependent Phosphorylation Regulates the Cell Surface Stability and Activity of the Potassium Chloride Cotransporter KCC2*
The potassium chloride cotransporter KCC2 plays a major role in the maintenance of transmembrane chloride potential in mature… 
Review
2007
Review
2007
Functional significance of channels and transporters expressed in the inner ear and kidney.
A number of ion channels and transporters are expressed in both the inner ear and kidney. In the inner ear, K(+) cycling and… 
Highly Cited
2007
Highly Cited
2007
Identification and functional characterization of cation-chloride cotransporters in plants.
Chloride (Cl(-)) is an essential nutrient and one of the most abundant inorganic anions in plant tissues. We have cloned an… 
Review
2005
Review
2005
Two developmental switches in GABAergic signalling: the K+–Cl− cotransporter KCC2 and carbonic anhydrase CAVII
GABAergic signalling has the unique property of ‘ionic plasticity’, which is based on short‐term and long‐term changes in the Cl… 
Highly Cited
1999
Highly Cited
1999
Cloning and Characterization of KCC3 and KCC4, New Members of the Cation-Chloride Cotransporter Gene Family*
The K+-Cl−cotransporters (KCCs) belong to the gene family of electroneutral cation-chloride cotransporters, which also includes… 
Highly Cited
1999
Highly Cited
1999
Regulation of Intracellular Chloride by Cotransporters in Developing Lateral Superior Olive Neurons
The regulatory mechanisms of intracellular Cl−concentration ([Cl−]i) were investigated in the lateral superior olive (LSO… 
Highly Cited
1997
Highly Cited
1997
Functional characterization of the neuronal-specific K-Cl cotransporter: implications for [K+]oregulation.
  • J. A. Payne
  • American Journal of Physiology - Cell Physiology
  • 1997
  • Corpus ID: 4406443
The neuronal K-Cl cotransporter isoform (KCC2) was functionally expressed in human embryonic kidney (HEK-293) cell lines. Two… 
Highly Cited
1997
Highly Cited
1997
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1).
We report identification of a new human nucleoside transporter protein by molecular cloning and functional expression of its cDNA… 
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