seocalcitol

Known as: (1R-(1alpha(1R*,2E,4E),3abeta,4E(1R*,3S*,5Z),7aalpha))-5-((1-(6-Ethyl-6-hydroxy-1-methyl-2,4-octadienyl)octahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-4-methylene-1,3-cyclohexanediol, 1(S),3(R)-dihydroxy-20(R)-(5'-ethyl-5'-hydroxyhepta-1'(E),3'(E)-dien-1'-yl)-9,10-secopregna-5(Z),7(E),10(19)-triene 
A vitamin D3 analogue with potential antineoplastic activity. Seocalcitol binds to and activates the vitamin D receptor, a cytoplasmic polypeptide… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2017
012320002017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
The bioavailability of seocalcitol from two lipid-based formulations and a propylene glycol (PG) solution was studied in minipigs… (More)
Is this relevant?
2006
2006
By constructing ternary phase diagrams it was possible to identify two self-microemulsifying drug delivery systems (SMEDDS… (More)
Is this relevant?
2006
2006
To study the use of long chain triglycerides (LCT) as a lymphotropic carrier of 3H-seocalcitol by comparing the lymphatic… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • table II
Is this relevant?
2005
2005
Simulated intestinal media (SIM) containing bile salt (BS) and phospholipids (PL) with and without medium chain lipolytic… (More)
Is this relevant?
2005
2005
BACKGROUND Transitional cell carcinoma (TCC) in dogs is associated with high morbidity and mortality. Calcitriol and its analog… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table I
Is this relevant?
2004
2004
The plethora of actions of 1alpha,25(OH)(2)D(3) in various systems suggested wide clinical applications of vitamin D nuclear… (More)
Is this relevant?
2003
2003
Hepatocellular carcinoma (HCC) is a common malignant tumour, which has a poor prognosis. Surgical resection can be curative but… (More)
  • table 2
  • table 1
  • figure 1
  • table 3
  • table 4
Is this relevant?
2003
2003
Although 1,25-dihydroxyvitamin D3 is a potent cell-differentiating agent, its use in cancer prevention or therapy is precluded… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Kaposi's sarcoma-associated herpesvirus is associated with three human tumors: Kaposi's sarcoma, and the B cell lymphomas… (More)
Is this relevant?
2002
2002
Inoperable cancer of the exocrine pancreas responds poorly to most conventional anti-cancer agents, and new agents are required… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?