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seocalcitol

Known as: (1R-(1alpha(1R*,2E,4E),3abeta,4E(1R*,3S*,5Z),7aalpha))-5-((1-(6-Ethyl-6-hydroxy-1-methyl-2,4-octadienyl)octahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-4-methylene-1,3-cyclohexanediol, 1(S),3(R)-Dihydroxy-20(R)-(5'-ethyl-5'-hydroxyhepta-1'(E),3'(E)-dien-1'-yl)-9,10-secopregna-5(Z),7(E),10(19)-triene 
A vitamin D3 analogue with potential antineoplastic activity. Seocalcitol binds to and activates the vitamin D receptor, a cytoplasmic polypeptide… Expand
National Institutes of Health

Papers overview

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2017
2017
Pathological growth of ocular vasculature networks can underpin visual impairment in neovascular age‐related macular degeneration… Expand
Review
2009
Review
2009
BACKGROUND Clinical guidelines recommend vitamin D compounds to suppress serum parathyroid hormone (PTH) in chronic kidney… Expand
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2007
2007
The bioavailability of seocalcitol from two lipid-based formulations and a propylene glycol (PG) solution was studied in minipigs… Expand
Highly Cited
2006
Highly Cited
2006
By constructing ternary phase diagrams it was possible to identify two self-microemulsifying drug delivery systems (SMEDDS… Expand
2005
2005
Simulated intestinal media (SIM) containing bile salt (BS) and phospholipids (PL) with and without medium chain lipolytic… Expand
Highly Cited
2003
Highly Cited
2003
Hepatocellular carcinoma (HCC) is a common malignant tumour, which has a poor prognosis. Surgical resection can be curative but… Expand
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Highly Cited
2003
Highly Cited
2003
Kaposi's sarcoma-associated herpesvirus is associated with three human tumors: Kaposi's sarcoma, and the B cell lymphomas… Expand
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Highly Cited
2002
Highly Cited
2002
Inoperable cancer of the exocrine pancreas responds poorly to most conventional anti-cancer agents, and new agents are required… Expand
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Review
2000
Review
2000
It is well established that the metabolically active form of vitamin D, 1alpha,25-dihydroxyvitamin D3 (1alpha,25(OH)2D3) plays a… Expand
2000
2000
A liquid chromatographic-tandem mass spectrometric assay in human and pig serum has been developed for quantitative analysis of… Expand