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EB 1089

Known as: EB-1089, EB1089 
 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
A chemotherapeutic vitamin D analogue, EB1089, kills tumor cells via a caspase-independent pathway that results in chromatin… Expand
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Highly Cited
2002
Highly Cited
2002
In the present study, we examined whether anti‐CD40+IL‐4‐mediated B cell proliferation and immunoglobulin synthesis is affected… Expand
Highly Cited
2002
Highly Cited
2002
Inoperable cancer of the exocrine pancreas responds poorly to most conventional anti-cancer agents, and new agents are required… Expand
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Highly Cited
2000
Highly Cited
2000
Vitamin D3 is believed to reduce the risk of colon cancer, and serum levels inversely correlate with colorectal cancer incidence… Expand
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Highly Cited
2000
Highly Cited
2000
1,25-Dihydroxyvitamin D has potent antiproliferative and anti-invasive properties in vitro in cancer cells. However, its calcemic… Expand
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Highly Cited
1999
Highly Cited
1999
The steroid hormone 1,25-dihydroxyvitamin D [1,25(OH)2D, also known as calcitriol] is known to inhibit the proliferation and to… Expand
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Highly Cited
1998
Highly Cited
1998
Preclinical studies have shown that the vitamin D analogue EB 1089 has significantly less calcaemic activity than its parent… Expand
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Highly Cited
1997
Highly Cited
1997
Recent studies have suggested that the active metabolite of vitamin D3, 1,25-dihydroxyvitamin D3, can inhibit the growth and/or… Expand
Highly Cited
1996
Highly Cited
1996
Vitamin D derivatives have been shown both to inhibit the proliferation of cultured breast cancer cells and to cause regression… Expand
Highly Cited
1992
Highly Cited
1992
EB1089 is a novel vitamin D analogue which has been tested for its effects on breast cancer cell growth in vitro, using the… Expand