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Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma.
- S. Wells, S. Asa, +15 authors S. Waguespack
- Thyroid : official journal of the American…
- 3 June 2015
The revised guidelines are focused primarily on the diagnosis and treatment of patients with sporadic medullary thyroid carcinoma (MTC) and hereditary MTC and developed 67 evidence-based recommendations to assist clinicians in the care of Patients with MTC. Expand
Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma: A Paradigm Shift to Reduce Overtreatment of Indolent Tumors.
Thyroid tumors currently diagnosed as noninvasive EFVPTC have a very low risk of adverse outcome and should be termed NIFTP, and this reclassification will affect a large population of patients worldwide and result in a significant reduction in psychological and clinical consequences associated with the diagnosis of cancer. Expand
Pathogenetic mechanisms in thyroid follicular-cell neoplasia
Defects in transcriptional and post-transcriptional regulation of adhesion molecules and cell-cycle control elements seem to affect tumour progression, and this information can provide powerful ancillary diagnostic tools and can also be used to identify new therapeutic targets. Expand
Comprehensive Characterization of Cancer Driver Genes and Mutations
This study reports a PanCancer and PanSoftware analysis spanning 9,423 tumor exomes (comprising all 33 of The Cancer Genome Atlas projects) and using 26 computational tools to catalog driver genes and mutations, identifying 299 driver genes with implications regarding their anatomical sites and cancer/cell types. Expand
Integrated Genomic Characterization of Papillary Thyroid Carcinoma
The genomic landscape of 496 PTCs is described and a reclassification of thyroid cancers into molecular subtypes that better reflect their underlying signaling and differentiation properties is proposed, which has the potential to improve their pathological classification and better inform the management of the disease. Expand
Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: A synopsis of the National Cancer Institute Thyroid Fine‐Needle Aspiration State of the Science Conference
This document summarizes matters regarding diagnostic terminology/classification scheme for thyroid FNA interpretation and cytomorphologic criteria for the diagnosis of various benign and malignant thyroid lesions. Expand
The American Association of Endocrine Surgeons Guidelines for Definitive Management of Primary Hyperparathyroidism.
Evidence-based recommendations were created to assist clinicians in the optimal treatment of patients with pHPT to develop evidence-based guidelines to enhance the appropriate, safe, and effective practice of parathyroidectomy. Expand
The prevalence of pituitary adenomas
The goals of the current study were to determine the prevalence of pituitary adenomas and to explore the clinical relevance of the findings. Expand
Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting.
- N. González-Cadavid, W. Taylor, +10 authors S. Bhasin
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 8 December 1998
The hypothesis that myostatin is an attenuator of skeletal muscle growth in adult men and contributes to muscle wasting in HIV-infected men is supported. Expand
Oncogenic Signaling Pathways in The Cancer Genome Atlas
This work charted the detailed landscape of pathway alterations in 33 cancer types, stratified into 64 subtypes, and identified patterns of co-occurrence and mutual exclusivity. Expand