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saxitoxinol

Known as: (3H)-saxitoxinol, STXOL, dihydrosaxitoxin 
National Institutes of Health

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Saxitoxin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Synthesis of saxitoxin derivatives bearing guanidine and urea groups at C13 and evaluation of their inhibitory activity on voltage-gated sodium channels.
Here, we describe the synthesis of the first C13-N-substituted STX derivatives 4, 5, and 6 bearing a guanidine, a urea group, and… 
1997
1997
Comparative binding and toxicity of saxitoxin and saxitoxinol in mice and in cultured cells
The binding characteristics of saxitoxin (STX), a known voltage‐gated sodium channel blocker, and its analog saxitoxinol (STXOL… 
1996
1996
Toxicokinetics of [3H]saxitoxinol in peripheral and central nervous system of rats.
1993
1993
[3H]-saxitoxinol metabolism and elimination in the rat.
1990
1990
Metabolism, excretion, and distribution of sup 3 H-saxitoxinol in the rat
Saxotoxin (STX) metabolism in mammalian systems remains uninvestigated, primarily because non-exchangeable radiolabeled STX has… 
1985
1985
Actions of epimers of 12-(OH)-reduced saxitoxin and of 11-(OSO3)-saxitoxin on squid axon.
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