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Potassium Currents in Freshly Dissociated Uterine Myocytes from Nonpregnant and Late-Pregnant Rats
In freshly dissociated uterine myocytes, the outward current is carried by K+ through channels highly selective for K+. Typically, nonpregnant myocytes have rather noisy K+ currents; half of themExpand
Sodium and Calcium Inward Currents in Freshly Dissociated Smooth Myocytes of Rat Uterus
Freshly dissociated myocytes from nonpregnant, pregnant, and postpartum rat uteri have been studied with the tight-seal patch-clamp method. The inward current contains both INa and ICa that areExpand
Structure‐Activity Relations of Tetrodotoxin, Saxitoxin, and Analogues a, b
  • C. Y. Kao
  • Chemistry, Medicine
  • Annals of the New York Academy of Sciences
  • 1 December 1986
Active groups of saxitoxin and tetrodotoxin as deduced from actions of saxitoxin analogues on frog muscle and squid axon.
1. The actions of three saxitoxin (STX) analogues have been studied on the frog sartorius muscle fibre and the squid giant axon. One‐‐neosaxitoxin‐‐is a natural analogue, and two‐‐decarbamylsaxitoxinExpand
Pharmacological studies on tarichatoxin, a potent neurotoxin.
Tarichatoxin, a purified substance with the probable molecular formula of C 11 H 17 N 3 O 8 can be obtained from the eggs of the California salamander, Taricha torosa. Upon parenteral administrationExpand
Refractoriness in cardiac muscle.
A preparation consisting of a papillary muscle and attached bundle of Purkinje fibers has been employed to study refractoriness of single cardiac fibers of the dog heart. Transmembrane stimulation ...
The structure of chiriquitoxin from the costa rican frog atelopus chiriquiensis
Abstract The structure of chiriquitoxin, a tetrodotoxin analog isolated from the Costa Rican frog Atelopus chiriquiensis , was elucidated on the basis of NMR data. In the structure 11-CH2OH ofExpand
Permeation, selectivity, and blockade of the Ca2+-activated potassium channel of the guinea pig taenia coli myocyte
The permeation properties of the 147-pS Ca2+-activated K+ channel of the taenia coli myocytes are similar to those of the delayed rectifier channel in other excitable membranes. It has a selectivityExpand