Skip to search formSkip to main contentSkip to account menu

sarpogrelate

Known as: 2-(dimethylamino)-1-((2-(3-methoxyphenyl)phenoxy)methyl)ethyl hydrogensuccinate hydrochloride, mono-(2-(dimethylamino)-1-((2-(2-(3-methoxyphenyl)ethyl)phenoxy)methyl)ethyl)succinate hydrochloride 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Fibrinolytic AgentsPlatelet Aggregation InhibitorsSerotonin AntagonistsSuccinates

Narrower (1)

MCI 9042

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
5-Hydroxytryptamine induces cyclooxygenase-2 in rat vascular smooth muscle cells: Mechanisms involving Src, PKC and MAPK activation [corrected].
2006
2006
Inverse agonist activity of sarpogrelate, a selective 5-HT2A-receptor antagonist, at the constitutively active human 5-HT2A receptor.
Mutations producing constitutively active G-protein coupled receptors have been found in the pathophysiology of several diseases… 
2006
2006
Sarpogrelate, a 5-HT2A receptor antagonist in intermittent claudication. A Phase II European study
This was a multinational, multicentre, double-blind Phase II study in Europe to evaluate the efficacy and safety of two dose… 
2005
2005
Protective effects of sarpogrelate, a 5-HT2A antagonist, against postischemic myocardial dysfunction in guinea-pig hearts
The protective effects of sarpogrelate (SG), a 5-HT2A antagonist, were investigated in perfused guinea-pig Langendorff hearts… 
2002
2002
Binding and Functional Affinity of Sarpogrelate, Its Metabolite M-1 and Ketanserin for Human Recombinant Alpha-1-Adrenoceptor Subtypes
Serotonin (5-HT2) antagonists show high affinity for the α1-adrenoceptor (α1-AR) in addition to the 5-HT2 receptor. In the… 
2002
2002
Sarpogrelate, a specific 5ht2‐receptor antagonist, improves the coronary microcirculation in coronary artery disease
Background: Serotonin (5‐hydroxytryptamine: 5‐HT) reduces the coronary blood flow (CBF) as a product of aggregating platelets… 
2001
2001
Serotonin potentiates angiotensin II--induced vascular smooth muscle cell proliferation.
2001
2001
Effects of sarpogrelate hydrochloride on adenosine diphosphate- or collagen-induced platelet responses in arteriosclerosis obliterans
To evaluate the effects of the 5-HT2 receptor antagonist sarpogrelate hydrochloride (sarpogrelate) on platelet responses in… 
2000
2000
Enhanced serotonin-mediated responses in the nucleus tractus solitarius of spontaneously hypertensive rats
2000
2000
Conjunctive Effects of the 5HT2 Receptor Antagonist, Sarpogrelate, on Thrombolysis with Modified Tissue Plasminogen Activator in Different Laser-Induced Thrombosis Models
The effect of the serotonin (5HT2) receptor antagonist, sarpogrelate, was compared with that of the selective thrombin inhibitor… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)