Succinates

Known as: Succinates [Chemical/Ingredient], succinate 
Derivatives of SUCCINIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,4-carboxy… (More)
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (44)

1,2,3-tri(methylsuccinyl)glycerol ester1,4-bis(2-ethylhexyl) sodium sulfosuccinate10-O-succinoylryanodol2,2-dimethylsuccinic acid
(More)
In Bloodagonistsantagonists & inhibitorschemical synthesis

Broader (1)

dicarboxylate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Formation of propionate and butyrate by the human colonic microbiota.
The human gut microbiota ferments dietary non-digestible carbohydrates into short-chain fatty acids (SCFA). These microbial… (More)
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
Vascularization is essential for tissue development and in restoration of tissue integrity after an ischemic injury. In studies… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2007
Review
2007
Prospects for a bio-based succinate industry
Bio-based succinate is receiving increasing attention as a potential intermediary feedstock for replacing a large petrochemical… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells.
Succinate dehydrogenase (SDH) and fumarate hydratase (FH) are components of the tricarboxylic acid (TCA) cycle and tumor… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Histone demethylation by a family of JmjC domain-containing proteins
Covalent modification of histones has an important role in regulating chromatin dynamics and transcription. Whereas most covalent… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain.
Although metformin is widely used for the treatment of non-insulin-dependent diabetes, its mode of action remains unclear. Here… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
The Sod2 gene for Mn–superoxide dismutase (MnSOD), an intramitochondrial free radical scavenging enzyme that is the first line of… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.
A cytokine that can synergize with interleukin 2 to activate cytotoxic lymphocytes was purified to homogeneity. The protein… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1973
Highly Cited
1973
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen.
1. Pigeon heart mitochondria produce H(2)O(2) at a maximal rate of about 20nmol/min per mg of protein. 2. Succinate-glutamate and… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?