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saquinavir mesylate

Known as: Monomethanesulfonate, Saquinavir, Saquinavir Monomethanesulfonate, Saquinavir Monomethanesulfonate [Chemical/Ingredient] 
A drug that belongs to the family of drugs called protease inhibitors. It interferes with the ability of a virus to make copies of itself.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Abstract The central nervous system (CNS) is an immunological privileged sanctuary site-providing reservoir for HIV-1 virus… Expand
2012
2012
Saquinavir is an anti-retroviral drug with very low oral bioavailability (e.g. 0.7-4.0%) due to its affinity toward efflux… Expand
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2008
2008
The current research evaluated the ability of hydroxybutenyl-beta-cyclodextrin (HBenBCD) to enhance saquinavir in vitro… Expand
Highly Cited
2004
Highly Cited
2004
AbstractPurpose. To investigate in vitro the mechanisms involved in the gastrointestinal absorption of the HIV protease inhibitor… Expand
Highly Cited
2004
Highly Cited
2004
Saquinavir mesylate (SQV) is the first-in-class and prototypical HIV protease inhibitor (PI) used in the treatment of HIV… Expand
Highly Cited
2002
Highly Cited
2002
ABSTRACT To determine if saquinavir mesylate (saquinavir) is a substrate of human multidrug resistance-associated protein 1… Expand
Highly Cited
2000
Highly Cited
2000
BACKGROUND Predictors of virological response to highly active antiretroviral therapy (HAART) have never been systematically… Expand
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Highly Cited
1998
Highly Cited
1998
Saquinavir, a peptidomimetic HIV protease inhibitor, has been shown to be effective in reducing patient viral load and reducing… Expand
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1993
1993
Bromocriptine is commonly used for the suppression of lactation in the postpartum period. Bromocriptine mesylate (2-bromo… Expand
Highly Cited
1990
Highly Cited
1990
A novel class of 21-aminosteroids has been developed. Compounds within this series are potent inhibitors of iron-dependent lipid… Expand