saquinavir mesylate

Known as: Monomethanesulfonate, Saquinavir, Saquinavir Monomethanesulfonate, Saquinavir Monomethanesulfonate [Chemical/Ingredient] 
A drug that belongs to the family of drugs called protease inhibitors. It interferes with the ability of a virus to make copies of itself.
National Institutes of Health

Papers overview

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2014
2014
The central nervous system (CNS) is an immunological privileged sanctuary site-providing reservoir for HIV-1 virus. Current anti… Expand
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2014
2014
Saquinavir mesylate (SM) is a protease inhibitor with activity against human immunodeficiency virus type 1 (HIV-1) and is… Expand
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2012
2012
Saquinavir is an anti-retroviral drug with very low oral bioavailability (e.g. 0.7-4.0%) due to its affinity toward efflux… Expand
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2008
2008
The current research evaluated the ability of hydroxybutenyl-beta-cyclodextrin (HBenBCD) to enhance saquinavir in vitro… Expand
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2006
2006
A phase I study was conducted to formally evaluate the steady-state pharmacokinetics (PK) of tenofovir disoproxil fumarate (TDF… Expand
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2004
2004
Saquinavir mesylate (SQV) is the first-in-class and prototypical HIV protease inhibitor (PI) used in the treatment of HIV… Expand
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2002
2002
To determine if saquinavir mesylate (saquinavir) is a substrate of human multidrug resistance-associated protein 1 (hMRP1 [ABCC1… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Predictors of virological response to highly active antiretroviral therapy (HAART) have never been systematically… Expand
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1998
1998
AbstractPurpose. To investigate in vitro the mechanisms involved in the gastrointestinal absorption of the HIV protease inhibitor… Expand
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Highly Cited
1998
Highly Cited
1998
Saquinavir, a peptidomimetic HIV protease inhibitor, has been shown to be effective in reducing patient viral load and reducing… Expand
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