Saquinavir

Known as: SQV, Saquinavir [Chemical/Ingredient], Saquinivir 
An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site. It is a highly specific inhibitor of HIV-1 and HIV-2 proteases… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To evaluate atazanavir/ritonavir (ATV/RTV) (300/100 mg) once daily, atazanavir/saquinavir (ATV/SQV) (400/1200 mg) once… (More)
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Highly Cited
2002
Highly Cited
2002
Herbal therapies are widely used, but there are few data on their interactions with conventional medications. This study… (More)
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Highly Cited
2002
Highly Cited
2002
Cancer cells frequently show high constitutive activity of the antiapoptotic transcription factor nuclear factor kappaB (NF… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT Use of antiretroviral drugs, including protease inhibitors, for treatment of human immunodeficiency virus (HIV) infection… (More)
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Highly Cited
1999
Highly Cited
1999
Combination antiretroviral therapy for HIV-1 infection has resulted in profound control of HIV replication in vivo, improved… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To describe a syndrome of peripheral lipodystrophy (fat wasting of the face, limbs and upper trunk), hyperlipidaemia… (More)
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Highly Cited
1998
Highly Cited
1998
Currently available HIV-1 protease inhibitors are potent agents in the therapy of HIV-1 infection. However, limited oral… (More)
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Highly Cited
1997
Highly Cited
1997
AIMS To compare the inhibitory potential of the HIV protease inhibitors saquinavir, ritonavir and indinavir against CYP1A2… (More)
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Highly Cited
1997
Highly Cited
1997
Saquinavir is a HIV protease inhibitor used in the treatment of patients with acquired immunodeficiency syndrome, but its use is… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND In patients with human immunodeficiency virus (HIV) infection, combined treatment with several agents may increase the… (More)
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