Skip to search formSkip to main contentSkip to account menu

ribosylhomocysteinase activity

Known as: LuxS, S-ribosylhomocysteinase activity, S-ribosylhomocysteine lyase activity 
Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine. [EC:4.4.1.21, RHEA:17756]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
covR Mediated Antibiofilm Activity of 3-Furancarboxaldehyde Increases the Virulence of Group A Streptococcus
Background Group A streptococcus (GAS, Streptococcus pyogenes), a multi-virulent, exclusive human pathogen responsible for… 
2015
2015
Engineering Giardia lamblia trimethylguanosine synthase (GlaTgs2) to transfer non-natural modifications to the RNA 5'-cap.
Trimethylguanosine synthase from Giardia lamblia (GlaTgs2) naturally catalyzes methyl transfer from S-adenosyl-L-methionine… 
Review
2012
Review
2012
Gene Network Homology in Prokaryotes Using a Similarity Search Approach: Queries of Quorum Sensing Signal Transduction
Bacterial cell-cell communication is mediated by small signaling molecules known as autoinducers. Importantly, autoinducer-2 (AI… 
2011
2011
Inhibition of LuxS by S-ribosylhomocysteine analogues containing a [4-aza]ribose ring.
2009
2009
Detection of Autoinducer-2 and Analysis of the Profile of luxS and pfs Transcription in Streptococcus suis Serotype 2
The only quorum sensing (QS) system shared by Gram-positive and Gram-negative bacteria involves the production of autoinducer-2… 
2007
2007
Functional quorum sensing systems affect biofilm formation and protein expression in Yersinia pestis.
Gram-negative bacteria predominantly use two types of quorum sensing (QS) systems--LuxI-LuxR, responsible for synthesis of N… 
Highly Cited
2006
Highly Cited
2006
Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase.
S-Ribosylhomocysteinase (LuxS) catalyzes the cleavage of the thioether linkage in S-ribosylhomocysteine (SRH) to produce… 
2006
2006
Characterization of autoinducer 2 signal in Eikenella corrodens and its role in biofilm formation.
Quorum sensing (QS) is a process by which bacteria communicate using secreted chemical signaling molecules called autoinducers… 
Highly Cited
2004
Highly Cited
2004
Synthesis of LuxS inhibitors targeting bacterial cell-cell communication.
[reaction: see text] Quorum sensing is a process by which bacteria sense cell density. This cell-cell communication process is… 
Highly Cited
2003
Highly Cited
2003
The luxS Gene of Streptococcus pyogenes Regulates Expression of Genes That Affect Internalization by Epithelial Cells
ABSTRACT The gram-positive pathogen Streptococcus pyogenes was recently reported to possess a homologue of the luxS gene that is… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)