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reverse transcriptase, Human immunodeficiency virus 1

Known as: HIV-1 reverse transcriptase, reverse transcriptase, HIV-1, reverse transcriptase, human immunodeficiency virus type 1 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

HIV Reverse TranscriptaseRNA-Directed DNA Polymerase

Narrower (1)

p66 pol gene product, HIV-1

Papers overview

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2014
2014
Biological Activity of Sporolides A and B from Salinispora tropica: in silico Target Prediction Using Ligand‐Based Pharmacophore Mapping and in vitro activity Validation on HIV‐1 Reverse…
Sporolides A and B are novel polycyclic macrolides from the obligate marine actinomycetes, Salinispora tropica. The unique and… 
2011
2011
Towards an early diagnosis of HIV infection: an electrochemical approach for detection of HIV-1 reverse transcriptase enzyme.
Oriented for the rapid diagnosis of HIV infection, highly sensitive and facile electrochemical assays for HIV-1 reverse… 
2008
2008
Computational modeling of tetrahydroimidazo‐[4,5,1‐jk][1,4]‐benzodiazepinone derivatives: An atomistic drug design approach using Kier‐Hall electrotopological state (E‐state) indices
Quantitative structure‐activity relationships (QSAR), based on E‐state indices have been developed for a series of… 
2006
2006
Molecular docking studies on 4-thiazolidinones as HIV-1 RT inhibitors
AbstractFlexible docking simulations were performed on two series of 4-thiazolidinones as HIV-1 reverse transcriptase (HIV-1 RT… 
2005
2005
Comparison of ligand-based and structure-based 3D-QSAR approaches: a case study on (aryl-)bridged 2-aminobenzonitriles inhibiting HIV-1 reverse transcriptase.
Ligand- (GRIND) and structure-based (GLUE/GRIND) 3D-QSAR approaches were compared for 55 (aryl-)bridged 2-aminobenzonitriles… 
2003
2003
Activity predictions for efavirenz analogues with the K103N mutant of HIV reverse transcriptase.
2001
2001
HIV-1 reverse transcriptase interaction with model RNA-DNA duplexes.
HIV-1 reverse transcriptase (HIV-1 RT) is a multifunctional enzyme responsible for converting viral RNA into preintegrative DNA… 
2000
2000
Screening of selected plant extracts for in vitro inhibitory activity on HIV-1 reverse transcriptase (HIV-1 RT).
Methanolic-aqueous extracts of 70 plants were investigated for their ability to inhibit HIV-1 reverse transcriptase activity in… 
1999
1999
Quantitative structure-activity relationships and comparative molecular field analysis of TIBO derivatised HIV-1 reverse transcriptase inhibitors
Quantitative structure-activity relationships (QSAR) and Comparative Molecular Field Analysis (CoMFA) have been applied in order… 
1992
1992
The observed inhibitory potency of 3'-azido-3'-deoxythymidine 5'-triphosphate for HIV-1 reverse transcriptase depends on the length of the poly(rA) region of the template.
The inhibitory potency of 3'-azido-3'-deoxythymidine 5'-triphosphate (AZTTP) against HIV-1 reverse transcriptase (HIV-1 RT) has… 
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