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reverse transcriptase, Human immunodeficiency virus 1
Known as:
HIV-1 reverse transcriptase
, reverse transcriptase, HIV-1
, reverse transcriptase, human immunodeficiency virus type 1
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
HIV Reverse Transcriptase
RNA-Directed DNA Polymerase
Narrower (1)
p66 pol gene product, HIV-1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Biological Activity of Sporolides A and B from Salinispora tropica: in silico Target Prediction Using Ligand‐Based Pharmacophore Mapping and in vitro activity Validation on HIV‐1 Reverse…
Kesavan Dineshkumar
,
Vasudevan Aparna
,
Kantilal Z. Madhuri
,
W. Hopper
Chemical Biology and Drug Design
2014
Corpus ID: 6376337
Sporolides A and B are novel polycyclic macrolides from the obligate marine actinomycetes, Salinispora tropica. The unique and…
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2011
2011
Towards an early diagnosis of HIV infection: an electrochemical approach for detection of HIV-1 reverse transcriptase enzyme.
Mahmoud Labib
,
Patrick O. Shipman
,
S. Martic
,
H. Kraatz
In Analysis
2011
Corpus ID: 27614262
Oriented for the rapid diagnosis of HIV infection, highly sensitive and facile electrochemical assays for HIV-1 reverse…
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2008
2008
Computational modeling of tetrahydroimidazo‐[4,5,1‐jk][1,4]‐benzodiazepinone derivatives: An atomistic drug design approach using Kier‐Hall electrotopological state (E‐state) indices
N. Sapre
,
N. Pancholi
,
Swagata Gupta
,
N. Sapre
Journal of Computational Chemistry
2008
Corpus ID: 22973346
Quantitative structure‐activity relationships (QSAR), based on E‐state indices have been developed for a series of…
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2006
2006
Molecular docking studies on 4-thiazolidinones as HIV-1 RT inhibitors
R. Rawal
,
Ashutosh Kumar
,
M. Siddiqi
,
S. Katti
Journal of Molecular Modeling
2006
Corpus ID: 7824619
AbstractFlexible docking simulations were performed on two series of 4-thiazolidinones as HIV-1 reverse transcriptase (HIV-1 RT…
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2005
2005
Comparison of ligand-based and structure-based 3D-QSAR approaches: a case study on (aryl-)bridged 2-aminobenzonitriles inhibiting HIV-1 reverse transcriptase.
Simone Sciabola
,
E. Carosati
,
Massimo Baroni
,
R. Mannhold
Journal of Medicinal Chemistry
2005
Corpus ID: 40396931
Ligand- (GRIND) and structure-based (GLUE/GRIND) 3D-QSAR approaches were compared for 55 (aryl-)bridged 2-aminobenzonitriles…
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2003
2003
Activity predictions for efavirenz analogues with the K103N mutant of HIV reverse transcriptase.
Marina Udier-Blagović
,
E. Watkins
,
J. Tirado-Rives
,
W. L. Jorgensen
Bioorganic & Medicinal Chemistry Letters
2003
Corpus ID: 25325977
2001
2001
HIV-1 reverse transcriptase interaction with model RNA-DNA duplexes.
I. Gorshkova
,
J. Rausch
,
S. L. Le Grice
,
R. Crouch
Analytical Biochemistry
2001
Corpus ID: 43480384
HIV-1 reverse transcriptase (HIV-1 RT) is a multifunctional enzyme responsible for converting viral RNA into preintegrative DNA…
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2000
2000
Screening of selected plant extracts for in vitro inhibitory activity on HIV-1 reverse transcriptase (HIV-1 RT).
A. Mlinarič
,
S. Kreft
,
A. Umek
,
B. Strukelj
Pharmazie
2000
Corpus ID: 43258382
Methanolic-aqueous extracts of 70 plants were investigated for their ability to inhibit HIV-1 reverse transcriptase activity in…
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1999
1999
Quantitative structure-activity relationships and comparative molecular field analysis of TIBO derivatised HIV-1 reverse transcriptase inhibitors
S. Hannongbua
,
P. Pungpo
,
J. Limtrakul
,
P. Wolschann
J. Comput. Aided Mol. Des.
1999
Corpus ID: 42095047
Quantitative structure-activity relationships (QSAR) and Comparative Molecular Field Analysis (CoMFA) have been applied in order…
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1992
1992
The observed inhibitory potency of 3'-azido-3'-deoxythymidine 5'-triphosphate for HIV-1 reverse transcriptase depends on the length of the poly(rA) region of the template.
Q. F. Ma
,
I. Bathurst
,
P. Barr
,
G. L. Kenyon
Biochemistry
1992
Corpus ID: 45885673
The inhibitory potency of 3'-azido-3'-deoxythymidine 5'-triphosphate (AZTTP) against HIV-1 reverse transcriptase (HIV-1 RT) has…
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