HIV Reverse Transcriptase

Known as: Transcriptase, HIV Reverse, Reverse Transcriptase, HIV, HIV Reverse Transcriptase [Chemical/Ingredient] 
A reverse transcriptase encoded by the POL GENE of HIV. It is a heterodimer of 66 kDa and 51 kDa subunits that are derived from a common precursor… (More)
National Institutes of Health

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reverse transcriptase, Human immunodeficiency virus 1

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Highly Cited
2008
Highly Cited
2008
Dynamic binding orientations direct activity of HIV reverse transcriptase
The reverse transcriptase of human immunodeficiency virus (HIV) catalyses a series of reactions to convert the single-stranded… (More)
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Highly Cited
2008
Highly Cited
2008
Slide into action: dynamic shuttling of HIV reverse transcriptase on nucleic acid substrates.
The reverse transcriptase (RT) of human immunodeficiency virus (HIV) catalyzes a series of reactions to convert single-stranded… (More)
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2007
2007
Rationally designed dual inhibitors of HIV reverse transcriptase and integrase.
Bifunctional inhibitors were designed and synthesized based on 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)a1 non… (More)
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Highly Cited
2003
Highly Cited
2003
Human immunodeficiency virus reverse transcriptase and protease sequence database
The HIV reverse transcriptase and protease sequence database is an on-line relational database that catalogues evolutionary and… (More)
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Highly Cited
2003
Highly Cited
2003
Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence.
Viral replication and latently infected cellular reservoirs persist in HIV-infected patients achieving undetectable plasma virus… (More)
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Review
2003
Review
2003
The effect of NNRTIs on HIV reverse transcriptase dimerization.
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are chemically diverse compounds that allosterically inhibit HIV-1… (More)
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2003
2003
An HIV reverse transcriptase-selective nucleoside chain terminator.
The synthesis of a 2',3'-dideoxynucleoside cytidine analogue, but one that lacks the O2-carbonyl, is described from 2… (More)
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Highly Cited
1999
Highly Cited
1999
Human Immunodeficiency Virus Reverse Transcriptase and Protease Sequence Database
The HIV RT and Protease Sequence Database is an on-line relational database that catalogues evolutionary and drug-related human… (More)
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Highly Cited
1992
Highly Cited
1992
Mechanism and fidelity of HIV reverse transcriptase.
We have examined the RNA-dependent and DNA-dependent polymerase and ribonuclease H catalytic activities of human immunodeficiency… (More)
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Highly Cited
1986
Highly Cited
1986
Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.
The thymidine analog 3'-azido-3'-deoxythymidine (BW A509U, azidothymidine) can inhibit human immunodeficiency virus (HIV… (More)
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