regulation of apoptotic process

Induction of DNA damage by UVB and UVA radiation may generate mutations and genomic instability leading to carcinogenesis… Expand

HER2 is a trans-membrane receptor tyrosine kinase that activates multiple growth-promoting signaling pathways including PI3K-AKT… Expand

We examined the effects of all-trans retinoic acid (ATRA) and lutein (a nonprovitamin A carotenoid), on apoptosis and… Expand

The NF-κB family of transcription factors are involved in the regulation of innate and adaptive immune functions associated with… Expand

Mice with a null mutation of the gene encoding interferon consensus sequence–binding protein (ICSBP) develop a disease with… Expand

The prostate gland requires androgenic steroids for its appropriate embryological formation and postpubertal growth and, once at… Expand

Familial Alzheimer's disease is transmitted as an autosomal dominant disorder and, in 5-10% of the cases, is caused by mutations… Expand

We have recently cloned a novel growth inhibitor and candidate tumor suppressor called p33ING1 (I. Garkavtsev et al., Nature… Expand

Using the ovary as a model system for studying the hormonal regulation of apoptosis, recent studies have revealed that the… Expand

Abstract Transforming growth factor-β1 (TGF-β1), which is induced in the prostate following castration, has been speculated to… Expand