regulation of apoptotic process
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Apoptosis is a cellular suicide program that plays a critical role in development and human diseases, including cancer. Cancer… Expand cFLIP (cellular FLICE-like inhibitory protein) is structurally related to caspase-8 but lacks proteolytic activity due to… Expand Induction of DNA damage by UVB and UVA radiation may generate mutations and genomic instability leading to carcinogenesis… Expand Abstract Inhibitors of Apoptosis (IAPs) are a family of proteins with various biological functions including regulation of innate… Expand Phytoestrogens exist in edible compounds commonly found in fruits or plants. For long times, phytoestrogens have been used for… Expand Transformation and malignant progression of prostate cancer is regulated by the inability of prostatic epithelial cells to… Expand The NF-κB family of transcription factors are involved in the regulation of innate and adaptive immune functions associated with… Expand Mice with a null mutation of the gene encoding interferon consensus sequence–binding protein (ICSBP) develop a disease with… Expand We have recently cloned a novel growth inhibitor and candidate tumor suppressor called p33ING1 (I. Garkavtsev et al., Nature… Expand Abstract Transforming growth factor-β1 (TGF-β1), which is induced in the prostate following castration, has been speculated to… Expand