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ras Proteins

Known as: ras Proteins [Chemical/Ingredient], protein ra, Ras protein 
Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a… Expand
National Institutes of Health

Related topics

Related topics

19 relations
Genes, rasIn BloodProcess of secretionRHOQ gene
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Narrower (9)

MRAS protein, humanRAS2 protein, S cerevisiaeRRAS protein, humanRRP22 protein, human
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
RAS Proteins and Their Regulators in Human Disease
RAS proteins are binary switches, cycling between ON and OFF states during signal transduction. These switches are normally… Expand
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Highly Cited
1991
Highly Cited
1991
Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
We have conducted a genetic screen for mutations that decrease the effectiveness of signaling by a protein tyrosine kinase, the… Expand
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Highly Cited
1990
Highly Cited
1990
Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins.
Ras proteins participate as a molecular switch in the early steps of the signal transduction pathway that is associated with cell… Expand
Highly Cited
1990
Highly Cited
1990
let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein
Genetic analysis previously suggested that the let-60 gene controls the switch between vulval and hypodermal cell fates during C… Expand
Highly Cited
1989
Highly Cited
1989
All ras proteins are polyisoprenylated but only some are palmitoylated
The C-terminal CAAX motif of the yeast mating factors is modified by proteolysis to remove the three terminal amino acids (-AAX… Expand
Highly Cited
1989
Highly Cited
1989
The effect of GTPase activating protein upon ras is inhibited by mitogenically responsive lipids.
Bacterially synthesized c-Ha-ras protein (Ras) was incubated with guanosine triphosphatase (GTPase) activating (GA) protein in… Expand
Highly Cited
1986
Highly Cited
1986
Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins.
Expression of the ras oncogene is thought to be one of the contributing events in the initiation of certain types of human cancer… Expand
Highly Cited
1986
Highly Cited
1986
Requirement for c-ras proteins during viral oncogene transformation
Many retroviral oncogenes have been classified into one of several categories based on structure, enzymology and cellular… Expand
Highly Cited
1984
Highly Cited
1984
Homologies between signal transducing G proteins and ras gene products.
The guanosine triphosphate-binding proteins (G proteins) found in a variety of tissues transduce signals generated by ligand… Expand
Highly Cited
1984
Highly Cited
1984
Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins
The ras genes, which were first identified by their presence in RNA tumor viruses and which belong to a highly conserved gene… Expand
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