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Genes, ras

Known as: gene ras, ras Genes, ras gene 
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine… 
National Institutes of Health

Related topics

Related topics

15 relations
Costello syndrome (disorder)Oncogene Protein p21(ras)Proto-Oncogene Proteins p21(ras)aspects of radiation effects

Narrower (8)

HRAS geneHRAS wt AlleleK-ras OncogeneKRAS gene

Papers overview

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1999
1999
H-ras and K-ras gene mutations in primary human soft tissue sarcoma: concomitant mutations of the ras genes.
ras gene mutations have been described with varying frequency in several types of human malignancies. To determine the incidence… 
Highly Cited
1999
Highly Cited
1999
Growth inhibition of human pancreatic cancer cell lines by anti‐sense oligonucleotides specific to mutated K‐ras genes
About 90% of human pancreatic cancers carry K‐ras point mutation, which may play an important role in tumorigenesis. We… 
Highly Cited
1998
Highly Cited
1998
Mutations of p53 and K-ras genes as prognostic factors for non-small cell lung cancer.
To evaluate the importance of mutations of p53 and K-ras genes in the prognosis of patients with non-small cell lung cancer, one… 
1994
1994
Isolation of two novel ras genes in Dictyostelium discoideum; evidence for a complex, developmentally regulated ras gene subfamily.
In Dictyostelium discoideum, three ras genes (rasD, rasG and rasB) and one ras-related gene (rap1) have been previously isolated… 
Review
1992
Review
1992
PCR-based approaches for detection of mutated ras genes.
T h e ras genes encode 21-kD GTPbinding proteins (p21 ras) that cycle between an inactive GDP-bound form and an active GTP-bound… 
Highly Cited
1991
Highly Cited
1991
Rapid and sensitive nonradioactive detection of mutant K-ras genes via 'enriched' PCR amplification.
We have developed a rapid and highly sensitive nonradioactive method for the detection of a mutant codon 12 human c-K-ras allele… 
Highly Cited
1989
Highly Cited
1989
Activated ras genes in human seminoma: evidence for tumor heterogeneity.
The incidence of mutations in cellular ras genes was determined in human seminoma, a germ cell tumor of the testis, with the aid… 
Highly Cited
1987
Highly Cited
1987
Opposing effects of a ras oncogene on growth factor-stimulated phosphoinositide hydrolysis: desensitization to platelet-derived growth factor and enhanced sensitivity to bradykinin.
Expression of a transforming Harvey or Kirsten ras gene caused opposing effects in the ability of platelet-derived growth factor… 
1986
1986
Extensive sequence homology of the goldfish ras gene to mammalian ras genes.
We cloned ras-related sequences from goldfish genomic libraries constructed as recombinants using the lambda phage. Restriction… 
Highly Cited
1984
Highly Cited
1984
Nucleotide sequence of two rasH related-genes isolated from the yeast Saccharomyces cerevisiae.
A complete nucleotide sequence of two ras-related yeast genes (c- rassc -1 and c- rassc -2) isolated from the yeast strain… 
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