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HRAS wt Allele

Known as: H-ras, RASH1, v-Ha-ras Harvey Rat Sarcoma Viral Oncogene Homolog wt Allele 
Human HRAS wild-type allele is located in the vicinity of 11p15.5 and is approximately 3 kb in length. This allele, which encodes GTPase HRas protein… Expand
National Institutes of Health

Related topics

Related topics

45 relations
11p15.5Angiogenesis PathwayAngiotensin II Signaling PathwayB Cell Receptor Signaling Pathway
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Broader (1)

Genes, ras

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging
The search for longevity‐determining genes in human has largely neglected the operation of genetic interactions. We have… Expand
2005
2005
H-ras immunohistochemical expression and molecular analysis of urinary bladder lesions in grazing adult cattle exposed to bracken fern.
Chronic ingestion of bracken fern (Pteridium spp.) by cattle produces upper alimentary tract and urinary bladder tumours causing… Expand
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Review
2000
Review
2000
The importance of being K-Ras.
The ras genes give rise to a family of related proteins that have strong transforming potential. Typical in vitro studies fail to… Expand
Highly Cited
2000
Highly Cited
2000
The HRAS1 minisatellite locus and risk of ovarian cancer.
Approximately 10% of ovarian cancers are due to mutations in highly penetrant inherited cancer susceptibility genes. The highly… Expand
Highly Cited
2000
Highly Cited
2000
Relationships of TP53 codon 72 and HRAS1 polymorphisms with lung cancer risk in an ethnically diverse population.
Tobacco smoking is a strong cause of lung cancer. However, because only a small proportion of smokers develop the disease, other… Expand
1997
1997
An allelic variant at the ATM locus is implicated in breast cancer susceptibility.
We have tested a simple procedure, disease association by locus stratification, for identifying breast cancer patients with… Expand
Highly Cited
1994
Highly Cited
1994
Frequency of H-ras mutations in human bladder cancer detected by direct sequencing.
OBJECTIVE To determine the frequency of mutations of the H-ras gene in transitional cell carcinomas of the human urinary bladder… Expand
Highly Cited
1993
Highly Cited
1993
An association between the risk of cancer and mutations in the HRAS1 minisatellite locus.
BACKGROUND The role of mutations in protooncogenes and their regulatory sequences in the pathogenesis of cancer is under close… Expand
Highly Cited
1993
Highly Cited
1993
Refinement of regional loss of heterozygosity for chromosome 11p15.5 in human breast tumors.
The familial association of breast cancer with other tumors such as rhabdomyosarcoma that show loss of heterozygosity (LOH) for… Expand
1989
1989
Loss of the same alleles of HRAS1 and D11S151 in two independent pancreatic cancers from a patient with multiple endocrine neoplasia type 1.
The DNAs from two independent pancreatic cancers (tumors 1 and 2) in a patient with multiple endocrine neoplasia type 1 were… Expand
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