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HRAS wt Allele

Known as: H-ras, RASH1, v-Ha-ras Harvey Rat Sarcoma Viral Oncogene Homolog wt Allele 
Human HRAS wild-type allele is located in the vicinity of 11p15.5 and is approximately 3 kb in length. This allele, which encodes GTPase HRas protein… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The search for longevity‐determining genes in human has largely neglected the operation of genetic interactions. We have… Expand
2005
2005
Chronic ingestion of bracken fern (Pteridium spp.) by cattle produces upper alimentary tract and urinary bladder tumours causing… Expand
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Review
2000
Review
2000
The ras genes give rise to a family of related proteins that have strong transforming potential. Typical in vitro studies fail to… Expand
Highly Cited
2000
Highly Cited
2000
Approximately 10% of ovarian cancers are due to mutations in highly penetrant inherited cancer susceptibility genes. The highly… Expand
Highly Cited
2000
Highly Cited
2000
Tobacco smoking is a strong cause of lung cancer. However, because only a small proportion of smokers develop the disease, other… Expand
1997
1997
We have tested a simple procedure, disease association by locus stratification, for identifying breast cancer patients with… Expand
Highly Cited
1994
Highly Cited
1994
OBJECTIVE To determine the frequency of mutations of the H-ras gene in transitional cell carcinomas of the human urinary bladder… Expand
Highly Cited
1993
Highly Cited
1993
BACKGROUND The role of mutations in protooncogenes and their regulatory sequences in the pathogenesis of cancer is under close… Expand
Highly Cited
1993
Highly Cited
1993
The familial association of breast cancer with other tumors such as rhabdomyosarcoma that show loss of heterozygosity (LOH) for… Expand
1989
1989
The DNAs from two independent pancreatic cancers (tumors 1 and 2) in a patient with multiple endocrine neoplasia type 1 were… Expand