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quinupristin

Known as: N-((6R,9S,10R,13S,15aS,18R,22S,24aS)-22-(p-(Dimethylamino)benzyl)-6-ethyldocosahydro-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-18-(((3S)-3-quinuclidinylthio)methyl)-12H-pyrido(2,1-f)pyrrolo(2,1-l)(1,4,7,10,13,16)oxapentaazacyclononadecin-9-yl)-3-hydroxypicolinamide, Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic Acid)-,(S)-, quinupristin [Chemical/Ingredient] 
A semi-synthetic derivative of pristinamycin, a natural occurring type B streptogramin. Quinupristin binds to the bacterial 50S ribosomal subunit… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
  • J. Andrews
  • The Journal of antimicrobial chemotherapy
  • 2009
  • Corpus ID: 1760507
There have been considerable changes to the format of the recommendations since the previous version (version 7). The majority of… Expand
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Highly Cited
2005
Highly Cited
2005
Daptomycin is a cyclic lipopeptide antibiotic that has been available in the United States since September 2003. We report a… Expand
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Review
2004
Review
2004
Daptomycin is a novel cyclic lipopeptide antibiotic that provides rapid bactericidal activity against gram-positive pathogens in… Expand
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Highly Cited
2004
Highly Cited
2004
BackgroundThe bacterial ribosome is a primary target of several classes of antibiotics. Investigation of the structure of the… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Enterococcus faecalis isolates are resistant to clindamycin (CLI) and quinupristin-dalfopristin (Q-D), and this is… Expand
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Review
2001
Review
2001
  • S. Fridkin
  • Clinical infectious diseases : an official…
  • 2001
  • Corpus ID: 2981963
Ever since the first strain of Staphylococcus aureus with reduced susceptibility to vancomycin and teicoplanin was reported from… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT A total of 1,531 recent clinical isolates of Streptococcus pneumoniae were collected from 33 medical centers nationwide… Expand
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Highly Cited
2001
Highly Cited
2001
  • S. Gorbach
  • The New England journal of medicine
  • 2001
  • Corpus ID: 32952400
Antimicrobials have been used in food animals in North America and Europe for nearly half a century. Among the most common are… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT The in vitro activity of daptomycin was compared with those of vancomycin, linezolid, and quinupristin-dalfopristin… Expand
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Highly Cited
1999
Highly Cited
1999
A progressive increase in the incidence of vancomycin resistance in strains of Enterococcus faecium (VREF) has severely… Expand
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