quinupristin

Known as: N-((6R,9S,10R,13S,15aS,18R,22S,24aS)-22-(p-(Dimethylamino)benzyl)-6-ethyldocosahydro-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-18-(((3S)-3-quinuclidinylthio)methyl)-12H-pyrido(2,1-f)pyrrolo(2,1-l)(1,4,7,10,13,16)oxapentaazacyclononadecin-9-yl)-3-hydroxypicolinamide, Virginiamycin S1, 4-(4-(dimethylamino)-N-methyl-L-phenylalanine)-5-(5-((1-azabicyclo(2.2.2)oct-3-ylthio)methyl)-4-oxo-L-2-piperidinecarboxylic Acid)-,(S)-, quinupristin [Chemical/Ingredient] 
A semi-synthetic derivative of pristinamycin, a natural occurring type B streptogramin. Quinupristin binds to the bacterial 50S ribosomal subunit… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Mycobacterium abscessus infections tend to respond poorly to macrolide-based chemotherapy, even though the organisms appear to be… (More)
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Highly Cited
2004
Highly Cited
2004
A vancomycin-resistant Staphylococcus aureus (VRSA) isolate was obtained from a patient in Pennsylvania in September 2002… (More)
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Review
2003
Review
2003
Quinupristin-dalfopristin and linezolid demonstrate in vitro activity against a wide range of gram-positive bacteria, including… (More)
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Highly Cited
2001
Highly Cited
2001
The susceptibilities of Mycoplasma hominis, Mycoplasma pneumoniae, and Ureaplasma urealyticum to eight new antimicrobial agents… (More)
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Highly Cited
2001
Highly Cited
2001
A total of 1,531 recent clinical isolates of Streptococcus pneumoniae were collected from 33 medical centers nationwide during… (More)
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Highly Cited
2000
Highly Cited
2000
The in vitro activity of daptomycin was compared with those of vancomycin, linezolid, and quinupristin-dalfopristin against a… (More)
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2000
2000
To understand quinupristin-dalfopristin resistance among clinical isolates of gram-positive bacteria in Taiwan, where this agent… (More)
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Highly Cited
2000
Highly Cited
2000
Nosocomial pneumonia is a frequent complication in hospitalized patients. Gram-positive pathogens, particularly Staphylococcus… (More)
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Highly Cited
2000
Highly Cited
2000
Safety and efficacy of quinupristin-dalfopristin (an injectable streptogramin antibiotic) were evaluated in the treatment of a… (More)
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Highly Cited
1999
Highly Cited
1999
The relative frequency of 10 determinants of resistance to macrolides, lincosamides, and streptogramins was investigated by PCR… (More)
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