pyruvate dehydrogenase

 
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Hypoxia-inducible factor 1 (HIF-1) plays a key role in the reprogramming of cancer metabolism by activating transcription of… (More)
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Review
2009
Review
2009
Studies in Bristol in the 1960s and 1970s, led to the recognition that four mitochondrial dehydrogenases are activated by calcium… (More)
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Review
2009
Review
2009
Tumor cells fuel their metabolism with glucose and glutamine to meet the bioenergetic and biosynthetic demands of proliferation… (More)
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Highly Cited
2008
Highly Cited
2008
The advent of hyperpolarized (13)C magnetic resonance (MR) has provided new potential for the real-time visualization of in vivo… (More)
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Highly Cited
2007
Highly Cited
2007
Hypoxia is a pervasive microenvironmental factor that affects normal development as well as tumor progression. In most normal… (More)
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Highly Cited
2004
Highly Cited
2004
Mitochondria-produced reactive oxygen species (ROS) are thought to contribute to cell death caused by a multitude of pathological… (More)
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Highly Cited
2003
Highly Cited
2003
A computational procedure is described for assigning the absolute hand of the structure of a protein or assembly determined by… (More)
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Highly Cited
2002
Highly Cited
2002
The kinetics of furfural inhibition of the enzymes alcohol dehydrogenase (ADH; EC 1.1.1.1), aldehyde dehydrogenase (AlDH; EC 1.2… (More)
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Highly Cited
1998
Highly Cited
1998
Previous research has established that 4-hydroxy-2-nonenal (HNE), a highly toxic product of lipid peroxidation, is a potent… (More)
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Highly Cited
1996
Highly Cited
1996
To examine the mechanism by which lipids cause insulin resistance in humans, skeletal muscle glycogen and glucose-6-phosphate… (More)
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