Citric Acid Cycle

Known as: Szent-Gyorgyi-Krebs Cycle, Cycle, Citric Acid, The Krebs Cycle 
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons… (More)

Topic mentions per year

Topic mentions per year

1935-2018
020040060019352017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Altered glucose metabolism in cancer cells is termed the Warburg effect, which describes the propensity of most cancer cells to… (More)
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Highly Cited
2008
Highly Cited
2008
Mammalian cells fuel their growth and proliferation through the catabolism of two main substrates: glucose and glutamine. Most of… (More)
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Highly Cited
2008
Highly Cited
2008
Previous studies have suggested that insulin resistance develops secondary to diminished fat oxidation and resultant accumulation… (More)
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Highly Cited
2007
Highly Cited
2007
Antibiotic mode-of-action classification is based upon drug-target interaction and whether the resultant inhibition of cellular… (More)
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Highly Cited
2007
Highly Cited
2007
Tumor cell proliferation requires rapid synthesis of macromolecules including lipids, proteins, and nucleotides. Many tumor cells… (More)
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Highly Cited
2007
Highly Cited
2007
The stability and transcriptional activity of the hypoxia-inducible factors (HIFs) are regulated by two oxygen-dependent events… (More)
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Highly Cited
2006
Highly Cited
2006
Activation of glycolytic genes by HIF-1 is considered critical for metabolic adaptation to hypoxia through increased conversion… (More)
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Highly Cited
2006
Highly Cited
2006
The HIF-1 transcription factor drives hypoxic gene expression changes that are thought to be adaptive for cells exposed to a… (More)
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Highly Cited
2004
Highly Cited
2004
The citric acid cycle is central to the regulation of energy homeostasis and cell metabolism. Mutations in enzymes that catalyse… (More)
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1989
1989
The relationship of extramitochondrial Ca2+ to intramitochondrial Ca2+ and the influence of intramitochondrial free Ca2… (More)
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