Hydroperoxide metabolism in mammalian organs.
- B. Chance, H. Sies, A. Boveris
- BiologyPhysiological Reviews
- 1 July 1979
Oxidative stress: oxidants and antioxidants
- H. Sies
- BiologyExperimental Physiology
- 1 March 1997
These low molecular mass antioxidant molecules add significantly to the defense provided by the enzymes superoxide dismutase, catalase and glutathione peroxidases, which are termed ‘oxidative stress’.
Glutathione and its role in cellular functions.
- H. Sies
- BiologyFree Radical Biology & Medicine
- 1 November 1999
Oxidative stress: a concept in redox biology and medicine
- H. Sies
- Biology, ChemistryRedox Biology
- 2 January 2015
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
- H. Sies, Dean P. Jones
- BiologyNature reviews. Molecular cell biology
- 30 March 2020
This work focuses on ROS at physiological levels and their central role in redox signalling via different post-translational modifications, denoted as ‘oxidative eustress’.
Strategies of antioxidant defense
- H. Sies
- Biology
- 1 July 1993
Cellular protection against the deleterious effects of reactive oxidants generated in aerobic metabolism, called oxidative stress, is organized at multiple levels. Defense strategies include three…
Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples.
- T. Akerboom, H. Sies
- Biology, ChemistryMethods in Enzymology
- 1981
(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans.
- H. Schroeter, C. Heiss, M. Kelm
- Biology, MedicineProceedings of the National Academy of Sciences…
- 24 January 2006
The data demonstrate that the human ingestion of the flavanol (-)-epicatechin is, at least in part, causally linked to the reported vascular effects observed after the consumption of flavanol-rich cocoa.
Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress☆
- H. Sies
- ChemistryRedox Biology
- 5 January 2017
Oxidative stress: from basic research to clinical application.
- H. Sies
- BiologyAmerican Journal of Medicine
- 30 September 1991
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