DIHYDROLIPOAMIDE DEHYDROGENASE

Known as: Diaphorase, NAD, Dehydrogenase, Lipoic Acid, Lipoyl Dehydrogenase 
A flavoprotein containing oxidoreductase that catalyzes the reduction of lipoamide by NADH to yield dihydrolipoamide and NAD+. The enzyme is a… (More)
National Institutes of Health

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respiratory enzyme

Papers overview

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2013
2013
Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide.
Under oxidative stress conditions, mitochondria are the major site for cellular production of reactive oxygen species (ROS) such… (More)
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2010
2010
Roles of dihydrolipoamide dehydrogenase Lpd1 in Candida albicans filamentation.
Acetyl coenzyme A, a key intermediate of the mitochondrial carbon metabolism, is formed by the mitochondrial pyruvate… (More)
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Review
2007
Review
2007
Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer
The fraction of pyruvate dehydrogenase complex (PDC) in the active form is reduced by the activities of dedicated PD kinase… (More)
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Highly Cited
2004
Highly Cited
2004
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.
Mitochondria-produced reactive oxygen species (ROS) are thought to contribute to cell death caused by a multitude of pathological… (More)
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2000
2000
Inactivation of the stress- and starvation-inducible gls24 operon has a pleiotrophic effect on cell morphology, stress sensitivity, and gene expression in Enterococcus faecalis.
Enterococcus faecalis induces the synthesis of at least 42 proteins during 24 h of glucose starvation. Because of its induction… (More)
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1997
1997
Targeted disruption of the murine dihydrolipoamide dehydrogenase gene (Dld) results in perigastrulation lethality.
The Dld gene product, known as dihydrolipoamide dehydrogenase or the E3 component, catalyzes the oxidation of dihydrolipoyl… (More)
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1984
1984
Dihydrolipoamide dehydrogenase from halophilic archaebacteria.
Dihydrolipoamide dehydrogenase has been discovered in the halophilic archaebacteria for the first time. The enzyme from both… (More)
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Highly Cited
1979
Highly Cited
1979
Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide.
Thioredoxin from Escherichia coli was shown to catalyze the reduction of insulin disulfides by dithiothreitol. A quantitative… (More)
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Highly Cited
1972
Highly Cited
1972
The univalent reduction of oxygen by reduced flavins and quinones.
FMN and flavodoxin, when reduced by the action of ferredoxin-TPN+ oxidoreductase, have been shown to cause both univalent and… (More)
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Highly Cited
1968
Highly Cited
1968
ENZYMATIC PROPERTIES OF THE INNER AND OUTER MEMBRANES OF RAT LIVER MITOCHONDRIA
Treatment of rat liver mitochondria with digitonin followed by differential centrifugation was used to resolve the… (More)
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