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The origins and the future of microfluidics
- G. Whitesides
- Environmental Science, Medicine
- Nature
- 27 July 2006
The manipulation of fluids in channels with dimensions of tens of micrometres — microfluidics — has emerged as a distinct new field. Microfluidics has the potential to influence subject areas from… Expand
Soft Lithography.
- Y. Xia, G. Whitesides
- Medicine
- Angewandte Chemie
- 1998
Elastomeric stamps and molds provide a great opportunity to eliminate some of the disadvantages of photolithograpy, which is currently the leading technology for fabricating small structures. In the… Expand
Formation of droplets and bubbles in a microfluidic T-junction-scaling and mechanism of break-up.
- P. Garstecki, Michael J. Fuerstman, H. Stone, G. Whitesides
- Chemistry, Medicine
- Lab on a chip
- 24 February 2006
This article describes the process of formation of droplets and bubbles in microfluidic T-junction geometries. At low capillary numbers break-up is not dominated by shear stresses: experimental… Expand
Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).
- D. Duffy, J. C. Mcdonald, O. Schueller, G. Whitesides
- Chemistry, Medicine
- Analytical chemistry
- 24 October 1998
This paper describes a procedure that makes it possible to design and fabricate (including sealing) microfluidic systems in an elastomeric material [Formula: see text] poly(dimethylsiloxane) (PDMS)… Expand
Self-assembled monolayers of thiolates on metals as a form of nanotechnology.
- J. Love, L. Estroff, Jennah K. Kriebel, R. Nuzzo, G. Whitesides
- Chemistry, Medicine
- Chemical reviews
- 25 March 2005
Chaotic Mixer for Microchannels
- A. Stroock, S. Dertinger, A. Ajdari, I. Mezic, H. Stone, G. Whitesides
- Medicine
- Science
- 25 January 2002
It is difficult to mix solutions in microchannels. Under typical operating conditions, flows in these channels are laminar—the spontaneous fluctuations of velocity that tend to homogenize fluids in… Expand
Geometric control of cell life and death.
- C. Chen, M. Mrksich, S. Huang, G. Whitesides, D. Ingber
- Biology, Medicine
- Science
- 30 May 1997
Human and bovine capillary endothelial cells were switched from growth to apoptosis by using micropatterned substrates that contained extracellular matrix-coated adhesive islands of decreasing size… Expand
Fabrication of microfluidic systems in poly(dimethylsiloxane)
- J. C. Mcdonald, D. Duffy, +4 authors G. Whitesides
- Medicine
- Electrophoresis
- 2000
Microfluidic devices are finding increasing application as analytical systems, biomedical devices, tools for chemistry and biochemistry, and systems for fundamental research. Conventional methods of… Expand
Poly(dimethylsiloxane) as a material for fabricating microfluidic devices.
- J. C. Mcdonald, G. Whitesides
- Materials Science, Medicine
- Accounts of chemical research
- 24 April 2002
This Account summarizes techniques for fabrication and applications in biomedicine of microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS). The methods and applications described focus on… Expand
Self-Assembly at All Scales
- G. Whitesides, B. Grzybowski
- Medicine
- Science
- 29 March 2002
Self-assembly is the autonomous organization of components into patterns or structures without human intervention. Self-assembling processes are common throughout nature and technology. They involve… Expand
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