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The origins and the future of microfluidics
The manipulation of fluids in channels with dimensions of tens of micrometres — microfluidics — has emerged as a distinct new field. Microfluidics has the potential to influence subject areas from
Soft Lithography.
The current state of development in this promising area of research in "soft lithography" is presented here.
Formation of droplets and bubbles in a microfluidic T-junction-scaling and mechanism of break-up.
Experimental results support the assertion that the dominant contribution to the dynamics of break-up arises from the pressure drop across the emerging droplet or bubble.
Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).
A procedure that makes it possible to design and fabricate microfluidic systems in an elastomeric material poly(dimethylsiloxane) (PDMS) in less than 24 h by fabricating a miniaturized capillary electrophoresis system is described.
Chaotic Mixer for Microchannels
This work presents a passive method for mixing streams of steady pressure-driven flows in microchannels at low Reynolds number, and uses bas-relief structures on the floor of the channel that are easily fabricated with commonly used methods of planar lithography.
Geometric control of cell life and death.
Human and bovine capillary endothelial cells were switched from growth to apoptosis by using micropatterned substrates that contained extracellular matrix-coated adhesive islands of decreasing size
Fabrication of microfluidic systems in poly(dimethylsiloxane)
Fabrication of microfluidic devices in poly(dimethylsiloxane) (PDMS) by soft lithography provides faster, less expensive routes to devices that handle aqueous solutions.
Poly(dimethylsiloxane) as a material for fabricating microfluidic devices.
This Account summarizes techniques for fabrication and applications in biomedicine of microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS). The methods and applications described focus on
Self-Assembly at All Scales
Self-assembling processes are common throughout nature and technology and involve components from the molecular to the planetary scale and many different kinds of interactions.