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pyruvate dehydrogenase (acetyl-transferring) kinase

Known as: (pyruvate dehydrogenase (lipoamide))kinase, PDH kinase, pyruvate dehydrogenase kinase 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The unique metabolism of breast cancer cells provides interest in exploiting this phenomenon therapeutically. Metformin, a… 
Highly Cited
2011
Highly Cited
2011
Dichloroacetate (DCA), an inhibitor of pyruvate dehydrogenase kinase (PDK), has been recently demonstrated as a promising… 
Review
2010
Review
2010
Pulmonary arterial hypertension (PAH) is a syndrome in which pulmonary arterial obstruction increases pulmonary vascular… 
2010
2010
Aging presumably initiates shifts in substrate oxidation mediated in part by changes in insulin sensitivity. Similar shifts occur… 
Highly Cited
2009
Highly Cited
2009
  • S. DharS. Lippard
  • Proceedings of the National Academy of Sciences
  • 2009
  • Corpus ID: 187229
The unique glycolytic metabolism of most solid tumors, known as the Warburg effect, is associated with resistance to apoptosis… 
Highly Cited
2009
Highly Cited
2009
Background Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARα, -β/δ, and -γ) nuclear receptors. In… 
Highly Cited
2008
Highly Cited
2008
The heart adapts to changes in nutritional status and energy demands by adjusting its relative metabolism of carbohydrates and… 
Highly Cited
2008
Highly Cited
2008
A characteristic manifestation of sepsis is muscle lactate accumulation. This study examined any putative (causative) association… 
Highly Cited
2005
Highly Cited
2005
Cardiac ischemia and reperfusion are associated with loss in the activity of the mitochondrial enzyme pyruvate dehydrogenase (PDH…