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PDK2 gene

Known as: PDHK2, pyruvate dehydrogenase kinase 2, PYRUVATE DEHYDROGENASE KINASE, ISOENZYME 2 
National Institutes of Health

Papers overview

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Review
2005
Review
2005
Phosphatidylinositol-3-kinase (PI3K) is a lipid kinase and generates phosphatidylinositol-3,4,5-trisphosphate (PI(3, 4, 5)P3). PI… 
Highly Cited
2004
Highly Cited
2004
Akt (= protein kinase B), a subfamily of the AGC serine/threonine kinases, plays critical roles in survival, proliferation… 
Highly Cited
2001
Highly Cited
2001
Akt activation requires phosphorylation of Thr308 and Ser473 by 3-phosphoinositide-dependent kinase-1 and 2 (PDK1 and PDK2… 
Highly Cited
2001
Highly Cited
2001
The enzymic activity of the mammalian pyruvate dehydrogenase complex is regulated by the phosphorylation of three serine residues… 
Highly Cited
2001
Highly Cited
2001
Activity of the mammalian pyruvate dehydrogenase complex is regulated by phosphorylation-dephosphorylation of three specific… 
Highly Cited
1999
Highly Cited
1999
The PtdIns(3,4,5)P3-dependent activation of protein kinase B (PKB) by 3-phosphoinositide-dependent protein kinases-1 and -2 (PDK1… 
Highly Cited
1998
Highly Cited
1998
Tissue distribution and kinetic parameters for the four isoenzymes of pyruvate dehydrogenase kinase (PDK1, PDK2, PDK3 and PDK4… 
Highly Cited
1998
Highly Cited
1998
The serine-threonine kinase Akt is a downstream target of phosphoinositide 3-kinase (PI 3-kinase); it is activated by the…