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PDK2 gene

Known as: PDHK2, pyruvate dehydrogenase kinase 2, PYRUVATE DEHYDROGENASE KINASE, ISOENZYME 2 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Phosphatidylinositol-3-kinase (PI3K) is a lipid kinase and generates phosphatidylinositol-3,4,5-trisphosphate (PI(3, 4, 5)P3). PI… Expand
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Review
2004
Review
2004
Phosphatidylinositol-3 kinases, PI3Ks, constitute a lipid kinase family characterized by their ability to phosphorylate inositol… Expand
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Highly Cited
2004
Highly Cited
2004
Akt (= protein kinase B), a subfamily of the AGC serine/threonine kinases, plays critical roles in survival, proliferation… Expand
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Highly Cited
2001
Highly Cited
2001
Akt activation requires phosphorylation of Thr308 and Ser473 by 3-phosphoinositide-dependent kinase-1 and 2 (PDK1 and PDK2… Expand
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Highly Cited
2001
Highly Cited
2001
Activity of the mammalian pyruvate dehydrogenase complex is regulated by phosphorylation-dephosphorylation of three specific… Expand
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Highly Cited
2001
Highly Cited
2001
The increase in skeletal muscle pyruvate dehydrogenase kinase (PDK) activity was measured in skeletal muscle of six healthy males… Expand
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Highly Cited
1999
Highly Cited
1999
The PtdIns(3,4,5)P3-dependent activation of protein kinase B (PKB) by 3-phosphoinositide-dependent protein kinases-1 and -2 (PDK1… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Protein kinase B (PKB) is activated by phosphorylation of Thr308 and of Ser473. Thr308 is phosphorylated by the 3… Expand
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Highly Cited
1998
Highly Cited
1998
Tissue distribution and kinetic parameters for the four isoenzymes of pyruvate dehydrogenase kinase (PDK1, PDK2, PDK3 and PDK4… Expand
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Highly Cited
1998
Highly Cited
1998
The serine-threonine kinase Akt is a downstream target of phosphoinositide 3-kinase (PI 3-kinase); it is activated by the… Expand
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