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PDK1 protein, human
Known as:
PDK1 (pyruvate dehydrogenase kinase, isozyme 1), human
, Pyruvate Dehydrogenase Kinase Isoform 1
, Pyruvate Dehydrogenase Kinase, Isoenzyme 1
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[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (436 aa, ~49 kDa) is encoded by the human PDK1 gene. This protein is involved in…
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National Institutes of Health
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Related topics
Related topics
18 relations
B Cell Receptor Signaling Pathway
Carbohydrate Metabolism
Enzyme Gene
Mast/Stem Cell Growth Factor Receptor Signaling Pathway
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Broader (2)
pyruvate dehydrogenase (acetyl-transferring) kinase
pyruvate dehydrogenase kinase isoform 1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Modulation of PI3K/PTEN Pathway Does Not Affect Catalytic Activity of PDK1 in Jurkat Cells.
Keum-Jin Yang
,
L. Piao
,
+10 authors
Jongsun Park
Anticancer Research
2017
Corpus ID: 38850585
Unopposed phosphoinositide 3-kinase (PI3K) activity and 3-phosphoinositide production in Jurkat cells, due to a mutation in the…
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2014
2014
Simultaneous targeting of PI 3 Kδ and a PI 3 Kδ-dependent MEK 1 / 2-Erk 1 / 2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia
Xi Zhang
,
Ben-shang Li
,
+7 authors
Linghua Meng
2014
Corpus ID: 41072598
B cell acute lymphoblastic leukemia (B-ALL) is the most common hematological malignancy diagnosed in children, and blockade of…
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2013
2013
PLATELETS AND THROMBOPOIESIS PDK 1 regulates platelet activation and arterial thrombosis
Xue Chen
,
Yue Zhang
,
+7 authors
Junling Liu
2013
Corpus ID: 33162685
Platelets, which are derived from megakaryocytes, circulate in mammalian blood and play essential roles in hemostasis…
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2013
2013
Cross Talk between the Akt and p 38 Pathways in Macrophages Downstream of Toll-Like Receptor Signaling
V. A. McGuire
,
A. Gray
,
+13 authors
J. S. C. Arthura
2013
Corpus ID: 18984902
Victoria A. McGuire, Alexander Gray, Claire E. Monk, Susana G. Santos, Keunwook Lee, Anna Aubareda, Jonathan Crowe, Natalia…
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2012
2012
Induced PDK1 kinase activity suppresses apoptosis in intestinal epithelial cells by activating Akt signaling following polyamine depletion.
K. Keledjian
,
B. Marasa
,
Jian‐Ying Wang
,
J. Rao
International Journal of Clinical and…
2012
Corpus ID: 25908545
Apoptosis plays a critical role in the maintenance of gut mucosal homeostasis and is highly regulated by numerous factors…
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2010
2010
3-hetaryl-substituted pyrrolo [2,3-b] pyridin-derivative as PDK1 inhibitors
wird später genannt werden Erfinder
2010
Corpus ID: 109416315
2006
2006
PDK1-mediated IKKβ phosphorylation activates NF-κB signaling
Hiroshi Tanaka
,
N. Fujita
,
T. Tsuruo
2006
Corpus ID: 80318233
4837 The IκB kinase (IKK)/NF-κB and phosphatidylinositol-3-OH kinase (PI3K)/3-phosphoinositide-dependent protein kinase-1 (PDK1…
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2004
2004
Über mitochondriale und cytoplasmatische Isozyme der Malatdehydrogenase in der psoriatischen Hornschicht
S. Marghescu
Archiv fur klinische und experimentelle…
2004
Corpus ID: 25292425
SummaryMalate dehydrogenase activities were determined electrophoretically in psoriatic scales. 2 isozymes have been isolated…
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2002
2002
Role of PDK 1 in insulin-signaling pathway for glucose metabolism in 3 T 3L 1 adipocytes
Tetsuya Yamada
,
H. Katagiri
,
+6 authors
Y. Oka
2002
Corpus ID: 1205982
TETSUYA YAMADA,1,2 HIDEKI KATAGIRI,1 TOMOICHIRO ASANO,3 MASATOSHI TSURU,2 KOUICHI INUKAI,4 HIRAKU ONO,5 TATSUHIKO KODAMA,6…
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1964
1964
Über die Isozyme der sauren Phosphatase und ihre intracelluläre Lokalisation in der menschlichen und der Rattenleber
A. Reith
,
E. Schmidt
,
F. Schmidt
Klinische Wochenschrift
1964
Corpus ID: 37872252
ZusammenfassungWie in der Rattenleber, sind auch in der menschlichen Leber vier Isozyme der sauren Phosphatase, wenn auch in…
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