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pyroglutamyl-histidyl-glycine

Known as: Pyr-His-Gly, pyro-Glu-His-Gly-OH, pGlu-His-Gly 
 
National Institutes of Health

Related topics

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6 relations

Broader (5)

Antineoplastic AgentsAppetite DepressantsOligopeptidesPyrrolidonecarboxylic Acid
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analogs & derivatives

Papers overview

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2007
2007
Effects of TRH and TRH-like peptide pGLU-HIS-GLY-NH2 on adrenocortical cell proliferation in rats
The effects of three peptides—colon mitosis inhibitor (CMI), its amide, and thyroliberin (TRH)—on the adrenocortical cell… Expand
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2000
2000
TRH-R2 exhibits similar binding and acute signaling but distinct regulation and anatomic distribution compared with TRH-R1.
TRH (thyroliberin) is a tripeptide (pGlu-His-ProNH2) that signals via G protein-coupled receptors. Until recently, only a single… Expand
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1993
1993
The synthetic colon peptide pyroGlu-His-GlyOH inhibits growth of human colon carcinoma cells (HT-29) transplanted subcutaneously into athymic mice.
Growth inhibitory tripeptide, pyroGlu-His-GlyOH colon mitosis inhibitor (CMI), was recently isolated from water extracts of mouse… Expand
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1992
1992
Thyroliberin (TRH) increases thymus cell proliferation in rats
The effects of thyroliberin (TRH), a TRH-like tripeptide colon mitosis inhibitor (CMI), a somatostatin analog SMS 201-995 and… Expand
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1988
1988
An endogenous colon mitosis inhibitor and dietary calcium inhibit the increased colonic cell proliferation induced by cholic acid.
We have previously reported that a single intraperitoneal injection of the tripeptide pGlu-His-GlyOH (colon mitosis inhibitor… Expand
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1986
1986
Delineation of a particulate thyrotropin-releasing hormone-degrading enzyme in rat brain by the use of specific inhibitors of prolyl endopeptidase and pyroglutamyl peptide hydrolase.
The degradation of thyrotropin-releasing hormone in rat brain homogenates was studied in the presence of N-benzyloxycarbonyl… Expand
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1982
1982
Increased plasma levels of thyroid hormones in a frog Rana ridibunda following intravenous administration of TRH.
The vena abdominalis of pentobarbital anesthetized frogs (Rana ridibunda) was cannulated for injection and blood sampling. After… Expand
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1980
1980
Modification of the proline residue of TRH enhances biological activity and inhibits degradation.
An analogue of TRH with a modified proline residue (Pyr-His-MepNH2) has been synthesised and evaluated. In CNS, but not endocrine… Expand
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1979
1979
Satietin: A highly potent anorexogenic substance in human serum
Abstract A substance named satietin, capable of reducing food intake drastically in rats deprived of food for 96 hr, was… Expand
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1973
1973
Serum prolactin and TSH: effects of nursing and pyroGlu-His-ProNH2 administration in postpartum women.
Abstract Nursing induced a marked increase (up to 10-fold) in serum prolactin, but it had no measurable effect on the… Expand
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