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pyroglutamyl-histidyl-glycine

Known as: Pyr-His-Gly, pyro-Glu-His-Gly-OH, pGlu-His-Gly 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2018
0246819672018

Related topics

Related topics

6 relations

Broader (5)

Antineoplastic AgentsAppetite DepressantsOligopeptidesPyrrolidonecarboxylic Acid
(More)
analogs & derivatives

Related mentions per year

Related mentions per year

1939-2018
19401960198020002020
pyroglutamyl-histidyl-glycine
Antineoplastic Agents
Appetite Depressants
Oligopeptides
Pyrrolidonecarboxylic Acid
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes
Cholecystokinin (CCK) is a rapidly degraded gastrointestinal peptide that stimulates satiety and insulin secretion. We aimed to… (More)
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2012
2012
The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropes.
Three forms of serpinin peptides, serpinin (Ala26Leu), pyroglutaminated (pGlu)-serpinin (pGlu23Leu), and serpinin-Arg-Arg-Gly… (More)
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2012
2012
Serpinins: role in granule biogenesis, inhibition of cell death and cardiac function.
Serpinins are a family of peptides derived from proteolytic cleavage of the penultimate and the last pair of basic residues at… (More)
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2008
2008
Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ.
Modified amyloid beta (Abeta) peptides represent major constituents of the amyloid deposits in Alzheimer's disease and Down's… (More)
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2003
2003
The colon mitosis-inhibitor pyroglutamyl-histidyl-glycine alters expression of immediate-early cancer-related genes in HT-29 cells.
BACKGROUND The intestinal mitosis-inhibiting peptide pyroglu-His-GlyOH (pEHG), inhibits normal intestinal epithelial cells and… (More)
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2002
2002
Early oncogene mRNA expression in HT-29 cells treated with the endogenous colon mitosis inhibitor pyroglutamyl-histidyl-glycine.
BACKGROUND The tripeptide pyroGlu-His-GlyOH (pEHG), isolated from intestinal extracts (1), suppresses growth of human colonic… (More)
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1996
1996
Effects of TRH and TRH-like peptide pGLU-HIS-GLY-NH(2) on adrenocortical cell proliferation in rats.
The effects of three peptides-colon mitosis inhibitor (CMI), its amide, and thyroliberin (TRH)-on the adrenocortical cell… (More)
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1993
1993
The synthetic colon peptide pyroGlu-His-GlyOH inhibits growth of human colon carcinoma cells (HT-29) transplanted subcutaneously into athymic mice.
Growth inhibitory tripeptide, pyroGlu-His-GlyOH colon mitosis inhibitor (CMI), was recently isolated from water extracts of mouse… (More)
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1992
1992
Thyroliberin (TRH) increases thymus cell proliferation in rats.
The effects of thyroliberin (TRH), a TRH-like tripeptide colon mitosis inhibitor (CMI), a somatostatin analog SMS 201-995 and… (More)
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1988
1988
An endogenous colon mitosis inhibitor and dietary calcium inhibit the increased colonic cell proliferation induced by cholic acid.
We have previously reported that a single intraperitoneal injection of the tripeptide pGlu-His-GlyOH (colon mitosis inhibitor… (More)
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