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pyroglutamyl-histidyl-glycine
Known as:
Pyr-His-Gly
, pyro-Glu-His-Gly-OH
, pGlu-His-Gly
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National Institutes of Health
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Related topics
Related topics
6 relations
Broader (5)
Antineoplastic Agents
Appetite Depressants
Oligopeptides
Pyrrolidonecarboxylic Acid
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analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
The synthetic colon peptide pyroGlu-His-GlyOH inhibits growth of human colon carcinoma cells (HT-29) transplanted subcutaneously into athymic mice.
J. Paulsen
Carcinogenesis
1993
Corpus ID: 31218482
Growth inhibitory tripeptide, pyroGlu-His-GlyOH colon mitosis inhibitor (CMI), was recently isolated from water extracts of mouse…
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Highly Cited
1986
Highly Cited
1986
Delineation of a Particulate Thyrotropin‐Releasing Hormone‐Degrading Enzyme in Rat Brain by the Use of Specific Inhibitors of Prolyl Endopeptidase and Pyroglutamyl Peptide Hydrolase
T. Friedman
,
S. Wilk
Journal of Neurochemistry
1986
Corpus ID: 24815647
Abstract: The degradation of thyrotropin‐releasing hormone in rat brain homogenates was studied in the presence of N…
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1982
1982
Neuropharmacological evaluation of RX 77368—a stabilised analogue of thyrotropin-releasing hormone (TRH)
G. Metcalf
,
P. Dettmar
,
D. Fortune
,
A. G. Lynn
,
I. Tulloch
Regulatory Peptides
1982
Corpus ID: 140445
Highly Cited
1981
Highly Cited
1981
Behavioural effects of central and peripheral injection of various analogues and metabolites of Thyrotropin Releasing Hormone (TRH)
D. Heal
,
A. Sabbagh
,
M. Youdim
,
A. Green
Neuropharmacology
1981
Corpus ID: 46461429
1981
1981
Thyrotropin-releasing hormone (TRH) analogues show enhanced CNS selectivity because of increased biological stability
G. Metcalf
,
P. Dettmar
,
A. G. Lynn
,
D. Brewster
,
M. Havler
Regulatory Peptides
1981
Corpus ID: 40537316
1981
1981
Thyrotropin-Releasing Hormone Increases Plasma Levels of Glucagon, Insulin, Glucose and Free Fatty Acids in Rabbits
J. Knudtzon
Hormone and metabolic research = Hormon- und…
1981
Corpus ID: 23064385
in vivo
1981
1981
Effect of synthetic thyrotrophin-releasing hormone and its analogues on growth hormone secretion in the domestic fowl (Gallus domesticus).
C. Scanes
,
S. Harvey
,
B. Morgan
,
M. Hayes
Acta Endocrinologica
1981
Corpus ID: 46199278
Variations in plasma growth hormone (GH) concentrations following iv or sc administration of synthetic thyrotrophin-releasing…
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Highly Cited
1979
Highly Cited
1979
Satietin: A highly potent anorexogenic substance in human serum
J. Knoll
Physiology and Behavior
1979
Corpus ID: 41460163
1973
1973
Serum prolactin and TSH: effects of nursing and pyroGlu-His-ProNH2 administration in postpartum women.
K. Gautvik
,
B. Weintraub
,
C. Graeber
,
F. Maloof
,
J. Zuckerman
,
A. Tashjian
Journal of Clinical Endocrinology and Metabolism
1973
Corpus ID: 20231168
Abstract Nursing induced a marked increase (up to 10-fold) in serum prolactin, but it had no measurable effect on the…
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Highly Cited
1971
Highly Cited
1971
Synthetic TRF (thyrotropin releasing factor) analogues. II. pGlu-N3imMe-His-Pro-NH2: a synthetic analogue with specific activity greater than that of TRF2.
W. Vale
,
J. Rivier
,
R. Burgus
Endocrinology
1971
Corpus ID: 38774445
A series of synthetic analogues of TRF (thyrotropin releasing factor, pGlu-His-Pro-NH2) have been tested for biological activity…
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