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pyroglutamyl-histidyl-glycine

Known as: Pyr-His-Gly, pyro-Glu-His-Gly-OH, pGlu-His-Gly 
National Institutes of Health

Related topics

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6 relations

Broader (5)

Antineoplastic AgentsAppetite DepressantsOligopeptidesPyrrolidonecarboxylic Acid
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
The synthetic colon peptide pyroGlu-His-GlyOH inhibits growth of human colon carcinoma cells (HT-29) transplanted subcutaneously into athymic mice.
Growth inhibitory tripeptide, pyroGlu-His-GlyOH colon mitosis inhibitor (CMI), was recently isolated from water extracts of mouse… 
Highly Cited
1986
Highly Cited
1986
Delineation of a Particulate Thyrotropin‐Releasing Hormone‐Degrading Enzyme in Rat Brain by the Use of Specific Inhibitors of Prolyl Endopeptidase and Pyroglutamyl Peptide Hydrolase
Abstract: The degradation of thyrotropin‐releasing hormone in rat brain homogenates was studied in the presence of N… 
1982
1982
Neuropharmacological evaluation of RX 77368—a stabilised analogue of thyrotropin-releasing hormone (TRH)
Highly Cited
1981
Highly Cited
1981
Behavioural effects of central and peripheral injection of various analogues and metabolites of Thyrotropin Releasing Hormone (TRH)
1981
1981
Thyrotropin-releasing hormone (TRH) analogues show enhanced CNS selectivity because of increased biological stability
1981
1981
Thyrotropin-Releasing Hormone Increases Plasma Levels of Glucagon, Insulin, Glucose and Free Fatty Acids in Rabbits
  • J. Knudtzon
  • Hormone and metabolic research = Hormon- und…
  • 1981
  • Corpus ID: 23064385
in vivo 
1981
1981
Effect of synthetic thyrotrophin-releasing hormone and its analogues on growth hormone secretion in the domestic fowl (Gallus domesticus).
Variations in plasma growth hormone (GH) concentrations following iv or sc administration of synthetic thyrotrophin-releasing… 
Highly Cited
1979
Highly Cited
1979
Satietin: A highly potent anorexogenic substance in human serum
1973
1973
Serum prolactin and TSH: effects of nursing and pyroGlu-His-ProNH2 administration in postpartum women.
Abstract Nursing induced a marked increase (up to 10-fold) in serum prolactin, but it had no measurable effect on the… 
Highly Cited
1971
Highly Cited
1971
Synthetic TRF (thyrotropin releasing factor) analogues. II. pGlu-N3imMe-His-Pro-NH2: a synthetic analogue with specific activity greater than that of TRF2.
A series of synthetic analogues of TRF (thyrotropin releasing factor, pGlu-His-Pro-NH2) have been tested for biological activity… 
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