Skip to search formSkip to main contentSkip to account menu

pyroglutamyl-histidyl-glycine

Known as: Pyr-His-Gly, pyro-Glu-His-Gly-OH, pGlu-His-Gly 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (5)

Antineoplastic AgentsAppetite DepressantsOligopeptidesPyrrolidonecarboxylic Acid
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
TRH-R2 exhibits similar binding and acute signaling but distinct regulation and anatomic distribution compared with TRH-R1.
TRH (thyroliberin) is a tripeptide (pGlu-His-ProNH2) that signals via G protein-coupled receptors. Until recently, only a single… 
1988
1988
An endogenous colon mitosis inhibitor and dietary calcium inhibit the increased colonic cell proliferation induced by cholic acid.
We have previously reported that a single intraperitoneal injection of the tripeptide pGlu-His-GlyOH (colon mitosis inhibitor… 
Highly Cited
1986
Highly Cited
1986
Delineation of a Particulate Thyrotropin‐Releasing Hormone‐Degrading Enzyme in Rat Brain by the Use of Specific Inhibitors of Prolyl Endopeptidase and Pyroglutamyl Peptide Hydrolase
Abstract: The degradation of thyrotropin‐releasing hormone in rat brain homogenates was studied in the presence of N… 
Highly Cited
1982
Highly Cited
1982
Increased plasma levels of thyroid hormones in a frog Rana ridibunda following intravenous administration of TRH.
1982
1982
Neuropharmacological evaluation of RX 77368—a stabilised analogue of thyrotropin-releasing hormone (TRH)
Highly Cited
1981
Highly Cited
1981
Behavioural effects of central and peripheral injection of various analogues and metabolites of Thyrotropin Releasing Hormone (TRH)
1980
1980
Modification of the proline residue of TRH enhances biological activity and inhibits degradation.
Highly Cited
1979
Highly Cited
1979
Satietin: A highly potent anorexogenic substance in human serum
  • J. Knoll
  • Physiology & Behavior
  • 1979
  • Corpus ID: 41460163
1973
1973
Serum prolactin and TSH: effects of nursing and pyroGlu-His-ProNH2 administration in postpartum women.
Abstract Nursing induced a marked increase (up to 10-fold) in serum prolactin, but it had no measurable effect on the… 
Highly Cited
1971
Highly Cited
1971
Synthetic TRF (thyrotropin releasing factor) analogues. II. pGlu-N3imMe-His-Pro-NH2: a synthetic analogue with specific activity greater than that of TRF2.
A series of synthetic analogues of TRF (thyrotropin releasing factor, pGlu-His-Pro-NH2) have been tested for biological activity… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License