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TRH (thyroliberin) is a tripeptide (pGlu-His-ProNH2) that signals via G protein-coupled receptors. Until recently, only a single… Expand We have previously reported that a single intraperitoneal injection of the tripeptide pGlu-His-GlyOH (colon mitosis inhibitor… Expand Abstract: The degradation of thyrotropin‐releasing hormone in rat brain homogenates was studied in the presence of N… Expand The vena abdominalis of pentobarbital anesthetized frogs (Rana ridibunda) was cannulated for injection and blood sampling. After… Expand Bilateral injection of 2 biologically stable analogues of TRH, CG3509 (orotyl-His-Pro-NH2; 5 μg) or CG3703 (6-methyl-5-oxo… Expand TRH exerts both endocrinological and neuropharmacological actions. Two analogues of TRH, Pyr-His-Mep . NH2 (L-trans-3… Expand An analogue of TRH with a modified proline residue (Pyr-His-MepNH2) has been synthesised and evaluated. In CNS, but not endocrine… Expand Abstract A substance named satietin, capable of reducing food intake drastically in rats deprived of food for 96 hr, was… Expand Abstract Nursing induced a marked increase (up to 10-fold) in serum prolactin, but it had no measurable effect on the… Expand A series of synthetic analogues of TRF (thyrotropin releasing factor, pGlu-His-Pro-NH2) have been tested for biological activity… Expand