Pyrrolidonecarboxylic Acid

OBJECTIVE Metabolic profiling of small molecules offers a snapshot of physiological processes. To identify metabolic signatures… (More)

Human health relies on the composition of microbiota in an individual's gut and the synthesized metabolites that may alter the… (More)

We searched for peptidic ligands for orphan G protein-coupled receptors utilizing a human genome data base and identified a new… (More)

By using 1H- and 13C-NMR spectroscopy, an accumulation of sucrose and two cyclic amino acids [ectoine (1,4,5,6-tetrahydro-2… (More)

We report here the isolation of three members of a new family of antimicrobial peptides from the hemolymph of shrimps Penaeus… (More)

As part of our ongoing search for novel antimicrobial agents and their use in singular or combined drug therapy, we have isolated… (More)

Simple, effective protocols have been developed for manual and machine-assisted Boc-chemistry solid phase peptide synthesis on… (More)

An inhibitor of the high conductance, Ca2(+)-activated K+ channel (PK,Ca) has been purified to homogeneity from venom of the… (More)

A peptide which stimulates the contractile activity of the cockroach hindgut was isolated from head extracts of the cockroach… (More)

Gamma-Glutamyl-cysteine synthetase is inhibited by glutathione under conditions similar to those which prevail in vivo, thus… (More)