Pyrrolidonecarboxylic Acid

Known as: 5-Oxo-L-Proline, 5-Carboxy-2-Pyrrolidinone, 5-Oxopyrrolidine-2-Carboxylic Acid 
A cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism.
National Institutes of Health

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2013
2013
OBJECTIVE Metabolic profiling of small molecules offers a snapshot of physiological processes. To identify metabolic signatures… (More)
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2011
Highly Cited
2011
Human health relies on the composition of microbiota in an individual's gut and the synthesized metabolites that may alter the… (More)
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2003
Highly Cited
2003
We searched for peptidic ligands for orphan G protein-coupled receptors utilizing a human genome data base and identified a new… (More)
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1999
Highly Cited
1999
By using 1H- and 13C-NMR spectroscopy, an accumulation of sucrose and two cyclic amino acids [ectoine (1,4,5,6-tetrahydro-2… (More)
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1997
Highly Cited
1997
We report here the isolation of three members of a new family of antimicrobial peptides from the hemolymph of shrimps Penaeus… (More)
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1993
Highly Cited
1993
As part of our ongoing search for novel antimicrobial agents and their use in singular or combined drug therapy, we have isolated… (More)
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1992
Highly Cited
1992
Simple, effective protocols have been developed for manual and machine-assisted Boc-chemistry solid phase peptide synthesis on… (More)
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Highly Cited
1990
Highly Cited
1990
An inhibitor of the high conductance, Ca2(+)-activated K+ channel (PK,Ca) has been purified to homogeneity from venom of the… (More)
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1986
Highly Cited
1986
A peptide which stimulates the contractile activity of the cockroach hindgut was isolated from head extracts of the cockroach… (More)
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1975
Highly Cited
1975
Gamma-Glutamyl-cysteine synthetase is inhibited by glutathione under conditions similar to those which prevail in vivo, thus… (More)
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