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Some puzzling pharmacological effects of monoamine oxidase inhibitors.
QTL analysis of early-season cold tolerance in sorghum
Cool temperatures during the early-growing season are a major limitation to growing sorghum [Sorghum bicolor (L.) Moench] in temperate areas. Several landraces from China have been found to exhibit… Expand
The striatal dopamine dependency of life span in male rats. Longevity study with (−)deprenyl
- J. Knoll
- Biology, Medicine
- Mechanisms of Ageing and Development
- 31 December 1988
Long-term experiments on male rats revealed that better performers in the mating test are better learners in the shuttle box and the more active animals live significantly longer than their less… Expand
Plasma adrenocorticotropin concentration in healthy horses and in horses with clinical signs of hyperadrenocorticism.
Pituitary adenomas are commonly reported in older horses. The typical clinical signs associated with this condition, also known as equine Cushing's disease (ECD), are related to increased… Expand
Inductively Coupled Plasma-Atomic Emission Spectrometry: Analysis of Biological Materials and Soils for Major, Trace, and Ultra-Trace Elements
An inductively coupled plasma sustained in flowing argon and a permanently aligned all-glass coaxial pneumatic nebulizer are employed in the atomic emission mode with a direct-reading poly-chromator… Expand
Phenylisopropylmethylpropinylamine (E-250), a new spectrum psychic energizer.
Novel S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is not involved in floral scent production in…
- F. Negre, N. Kolosova, J. Knoll, C. Kish, Natalia Dudareva
- Medicine, Biology
- Archives of biochemistry and biophysics
- 15 October 2002
Using a functional genomic approach we have isolated and characterized a cDNA that encodes a salicylic acid carboxyl methyltransferase (SAMT) from Antirrhinum majus. The sequence of the protein… Expand
Evidence that acetylcholine released by gastrin and related polypeptides contributes to their effect on gastrointestinal motility.
Abstract Gastrin- and cholecystokinin-like polypeptides have been found to release acetylcholine from the Auerbach plexus of longitudinal muscle strips of guinea pig ileum. The evidence is consistent… Expand
(-)Deprenyl (selegiline), a catecholaminergic activity enhancer (CAE) substance acting in the brain.
- J. Knoll
- Medicine, Chemistry
- Pharmacology & toxicology
- 1 February 1998
beta-Phenylethylamine and its long acting derivatives, the amphetamines, are mixed-acting stimulants of the sympathetic system in the brain. They enhance the impulse propagation mediated release of… Expand
Selective inhibition of the "B form" of monoamine oxidase.
Deprenyl (phenyl-isopropyl-methyl-propinylamine) is a potent inhibitor of monoamine oxidase (MAO) and like the acetylenic type of inhibitors it induces irreversible inhibition of the enzyme. Its… Expand