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procathepsin D

Known as: pro-cathepsin D 
National Institutes of Health

Related topics

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2 relations

Broader (2)

CATHEPSIN DEnzyme Precursors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Proteomic profiling of N‐linked glycoproteins identifies ConA‐binding procathepsin D as a novel serum biomarker for hepatocellular carcinoma
The aim of this study was to identify novel biomarkers for the diagnosis of, and potential therapeutic targets for… 
Review
2012
Review
2012
Procathepsin D as a tumor marker, anti-cancer drug or screening agent.
Procathepsin D (pCD) is overexpressed and secreted by cells of various tumor types including breast and lung carcinomas… 
2011
2011
Procathepsin D and cytokines influence the proliferation of lung cancer cells.
Enzymatically inactive procathepsin D (pCD) has been established as an important factor in the development of lung cancer. In… 
Review
2009
Review
2009
Pleiotropic effects of cathepsin D.
Over the past decades, the paradigm that lysosomal enzymes participate only in non-specific protein degradation during cell death… 
Highly Cited
2008
Highly Cited
2008
The propeptide of cathepsin D increases proliferation, invasion and metastasis of breast cancer cells.
Expression and secretion of procathepsin D (pCD) increases proliferation, metastasis and progression of breast cancer but the… 
2007
2007
Depletion of procathepsin D gene expression by RNA interference – A potential therapeutic target for breast cancer
Elevated level of procathepsin D (pCD), a zymogen of lysosomal aspartic proteinase cathepsin D, is associated with highly… 
2007
2007
Ribozyme-targeting procathepsin D and its effect on invasion and growth of breast cancer cells: an implication in breast cancer therapy.
Procathepsin D (pCD), a zymogen of lysosomal aspartic peptidase cathepsin D, overexpression is correlated with highly invasive… 
2007
2007
Secretion of cytokines in breast cancer cells: the molecular mechanism of procathepsin D proliferative effects.
Procathepsin D (pCD) is a major secreted protein in estrogen receptor-positive (ER+) breast cancer cell lines. Several… 
2006
2006
Role of activation peptide of procathepsin D in proliferation and invasion of lung cancer cells.
BACKGROUND Procathepsin D (pCD) secreted by cancer cells, increases proliferation, metastasis and progression of breast cancer… 
1997
1997
Differential targeting and processing of procathepsin D in normal and transformed murine 3T3 fibroblasts
The kinetics of transport and the processing of procathepsin D (proCD), the precursor of a lysosomal aspartyl protease involved… 
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