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preproinsulin

Known as: Proinsulin, pre- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

InsulinProtein Precursors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Protective regulatory T cell generation in autoimmune diabetes by DNA covaccination with islet antigens and a selective CTLA-4 ligand.
2003
2003
Beta cell-specific CD80 (B7-1) expression disrupts tissue protection from autoantigen-specific CTL-mediated diabetes.
1994
1994
Developmentally regulated expression of the preproinsulin gene in the chicken embryo during gastrulation and neurulation.
Despite the absence of a pancreas, which develops between embryonic day 3 (E3) to E4, previous studies showed that insulin… 
1990
1990
Truncations of a secretory protein define minimum lengths required for binding to signal recognition particle and translocation across the endoplasmic reticulum membrane.
1989
1989
Xenopus laevis contains two nonallelic preproinsulin genes. cDNA cloning and evolutionary perspective.
We undertook the cloning of preproinsulin cDNAs from the South African clawed toad, Xenopus laevis, in order to study the role of… 
Highly Cited
1982
Highly Cited
1982
Cellular location affects protein stability in Escherichia coli.
We study the biosynthesis of preproinsulin and proinsulin in Escherichia coli by pulse-chase experiments. When E. coli is… 
Highly Cited
1981
Highly Cited
1981
Expression of simian virus 40-rat preproinsulin recombinants in monkey kidney cells: use of preproinsulin RNA processing signals.
The complete rat preproinsulin gene I was cloned into a simian virus 30 (SV 40) vector. Most of the late region of the viral… 
Highly Cited
1980
Highly Cited
1980
Nucleotide sequence of human preproinsulin complementary DNA.
Recombinant bacterial plasmids that contain DNA complementary to human preproinsulin messenger RNA have been constructed. One… 
Highly Cited
1980
Highly Cited
1980
Analysis of the regions flanking the human insulin gene and sequence of an Alu family member.
The regions around the human insulin gene have been studied by heteroduplex, hybridization and sequence analysis. These studies… 
1976
1976
Partial purification and characterization of the mRNA for rat preproinsulin.
Electrophoretically homogeneous messenger RNA for rat preproinsulin has been prepared from an islet cell tumor by the use of… 
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