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OBJECTIVE Observational studies show breaking up prolonged sitting has beneficial associations with cardiometabolic risk markers… Expand The broad expression of the insulin receptor suggests that the spectrum of insulin function has not been fully described. A cell… Expand Insulin and insulin-like growth factors (IGFs) are well known as key regulators of energy metabolism and growth. There is now… Expand ObjectivesMaintenance of normoglycemia with insulin reduces mortality and morbidity of critically ill patients. Here we report… Expand Hepatic gluconeogenesis is absolutely required for survival during prolonged fasting or starvation, but is inappropriately… Expand The signaling pathways used by insulin have been identified [M. White, Insulin Signaling Pathway, Sci. STKE (Connections Map, as… Expand OBJECTIVE
The oral glucose tolerance test (OGTT) has often been used to evaluate apparent insulin release and insulin resistance… Expand Insulin plays a key role in regulating a wide range of cellular processes. However, until recently little was known about the… Expand Background Reduced insulin sensitivity has been proposed as an important risk factor in the development of atherosclerosis… Expand The purpose of this study was to examine whether insulin's effect to vasodilate skeletal muscle vasculature is mediated by… Expand