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pregabalin

Known as: (S)-3-Isobutyl gaba, (S)-3-(aminomethyl)-5-methylhexanoic acid, S-(+)-3-isobutylgaba 
A 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. Although the… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
BACKGROUND Generalised anxiety disorder is a disease that can be associated with substantial dysfunction. Pharmacological… Expand
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Review
2019
Review
2019
BACKGROUND This review updates part of an earlier Cochrane Review titled "Pregabalin for acute and chronic pain in adults", and… Expand
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Review
2018
Review
2018
Background: Antiepileptic drugs (AEDs) are the mainstay of epilepsy treatment. Since 1989, 18 new AEDs have been licensed for… Expand
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Review
2010
Review
2010
Background and objectives:  This second European Federation of Neurological Societies Task Force aimed at updating the existing… Expand
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Review
2006
Review
2006
  • G. Sills
  • Current opinion in pharmacology
  • 2006
  • Corpus ID: 6808531
Gabapentin and pregabalin are structurally related compounds with recognized efficacy in the treatment of both epilepsy and… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Fibromyalgia syndrome (FMS) is characterized by widespread musculoskeletal pain and lowered pain threshold. Other… Expand
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Review
2004
Review
2004
Summary:  Pregabalin is a potent ligand for the alpha‐2‐delta subunit of voltage‐gated calcium channels in the central nervous… Expand
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Highly Cited
2003
Highly Cited
2003
Objective: To evaluate the efficacy and safety of pregabalin in the treatment of postherpetic neuralgia (PHN). Methods: The… Expand
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Highly Cited
2002
Highly Cited
2002
Gabapentin and pregabalin (S-(+)-3-isobutylgaba) produced concentration-dependent inhibitions of the K(+)-induced [Ca(2+)](i… Expand
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Highly Cited
2001
Highly Cited
2001
&NA; Pain intensity is frequently measured on an 11‐point pain intensity numerical rating scale (PI‐NRS), where 0=no pain and 10… Expand
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