pre-replicative complex location

Known as: nuclear pre-replicative complex, pre-replicative complex, eukaryotic pre-replicative complex 
A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
012319972016

Papers overview

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2012
2012
We have used micrococcal nuclease (MNase) digestion followed by deep sequencing in order to obtain a higher resolution map than… (More)
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Highly Cited
2010
Highly Cited
2010
The initiation of DNA synthesis is governed by the licensing of replication origins, which consists of assembling a pre… (More)
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2010
2010
To ensure genomic integrity, the genome must be duplicated exactly once per cell cycle. Disruption of replication licensing… (More)
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2009
2009
Eukaryotic initiator proteins form origin recognition complexes (ORCs) that bind to replication origins during most of the cell… (More)
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2009
2009
Polo-like kinase 1 (Plk1) plays several roles in mitosis, and it has been suggested to have a role in tumorigenesis. We have… (More)
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2006
2006
DNA replication must be tightly controlled during each cell cycle to prevent unscheduled replication and ensure proper genome… (More)
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2005
2005
The MCM2-MCM7 complex is an essential component of the prereplication complex (pre-RC), which is recruited by the cdc6 and cdt1… (More)
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2003
2003
Previous studies have shown that infection of G(0)-synchronized human fibroblasts by human cytomegalovirus (HCMV) results in a… (More)
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1998
1998
Eukaryotic cells ensure the stable propagation of their genome by coupling each round of DNA replication (S phase) to passage… (More)
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Highly Cited
1997
Highly Cited
1997
The Cdc6 protein is essential for the assembly of pre-replicative complexes (pre-RCs) at origins of DNA replication in the… (More)
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